Treatment of Benzodiazepine Dependence | New England Journal of Medicine Skip to main
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Classical pharmacological dependence accompanied by euphoria, clinical evidence of
tolerance and escalation of dosage are very rare with the benzodiazepines. However, there …

Benzodiazepine dependence is a frequent complication of regular prescriptions for 4 weeks
or longer, occurring in almost one-third of patients. Although it is also manifested by …

Benzodiazepine dependence could be prevented by adherence to recommendations for
short-term prescribing (2–4 weeks only when possible). Withdrawal of benzodiazepines …

Withdrawal of benzodiazepines is currently advised for long‐term benzodiazepine users
because of doubts about continued efficacy, risks of adverse effects, including dependence …

The benzodiazepines were developed in the 1950s, some introduced in the 1960s, and
many more since then. Pharmacologically, they are sedative/hypnotics akin to alcohol …

Although benzodiazepines are invaluable in the treatment of anxiety disorders, they have
some potential for abuse and may cause dependence or addiction. It is important to …

Benzodiazepines (BZDs) are among one of the most widely prescribed drug classes in the
United States. BZDs are a class of psychoactive drugs known for their depressant effect on …

Physiological dependence on benzodiazepines is accompanied by a withdrawal syndrome
which is typically characterized by sleep disturbance, irritability, increased tension and …

The treatment of anxiety has evolved through various phases. Currently, there is a growing
recognition that anxiety disorders are frequently chronic and/or recurrent. There is also less …