Short-term PM2. 5 exposure induces transient lung injury and repair

Y Li, B Lin, D Hao, Z Du, Q Wang, Z Song, X Li… - Journal of Hazardous …, 2023 - Elsevier
Exposure to fine atmospheric particulate matter (PM) is known to induce lung inflammation
and injury; however, the way in which sophisticated endogenous lung repair and …

Effects of short-term high-concentration exposure to PM2. 5 on pulmonary tissue damage and repair ability as well as innate immune events

Y Liu, J Xu, J Shi, Y Zhang, Y Ma, Q Zhang, Z Su… - Environmental …, 2023 - Elsevier
Short-term heavy air pollution still occurs frequently worldwide, especially during the winter
heating period in some developing countries, which is usually accompanied by the …

Differential contribution of bone marrow-derived infiltrating monocytes and resident macrophages to persistent lung inflammation in chronic air pollution exposure

RS Gangwar, V Vinayachandran, P Rengasamy… - Scientific reports, 2020 - nature.com
Chronic exposure to particulate matter< 2.5 µ (PM2. 5) has been linked to cardiopulmonary
disease. Tissue-resident (TR) alveolar macrophages (A Φ) are long-lived, self-renew and …

Integrative characterization of fine particulate matter-induced chronic obstructive pulmonary disease in mice

Q Li, J Sun, X Chen, S Li, Y Wang, C Xu, J Zhao… - Science of The Total …, 2020 - Elsevier
The impacts of ambient fine particulate matter (PM 2.5) on public health are a worldwide
concern. Epidemiological evidence has shown that PM 2.5-triggered inflammatory cascades …

Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure

R Zhang, S Chen, L Chen, L Ye, Y Jiang… - Particle and fibre …, 2022 - Springer
Background Long-term exposure to fine particulate matter (PM2. 5) increases susceptibility
to chronic respiratory diseases, including inflammation and interstitial fibrosis. However, the …

Effect of PM2. 5 environmental pollution on rat lung

B Yang, J Guo, C Xiao - Environmental Science and Pollution Research, 2018 - Springer
Particulate matter smaller than 2.5 μm (PM2. 5) is a continuing challenge to pulmonary
health. Here, we investigated the mechanisms involved in PM2. 5 exposure-induced acute …

Fine particulate matter (PM2. 5) induces inhibitory memory alveolar macrophages through the AhR/IL-33 pathway

Y Liu, Q Yuan, X Zhang, Z Chen, X Jia, M Wang, T Xu… - Cellular …, 2023 - Elsevier
Abstract Fine particulate matter (PM2. 5) concentrations have decreased in the past decade.
The adverse effects of acute PM2. 5 exposure on respiratory diseases have been well …

Co-culture of human alveolar epithelial (A549) and macrophage (THP-1) cells to study the potential toxicity of ambient PM2.5: a comparison of growth under ALI and …

G Wang, X Zhang, X Liu, J Zheng - Toxicology Research, 2020 - academic.oup.com
Abstract Fine particulate matter (PM2. 5) in the ambient atmosphere is strongly associated
with detrimental health effects. However, these particles from various sources and regions …

Chronic lung inflammation and pulmonary fibrosis after multiple intranasal instillation of PM2.5 in mice

M Xu, X Wang, L Xu, H Zhang, C Li, Q Liu… - Environmental …, 2021 - Wiley Online Library
Abstract Fine particulate matter (PM2. 5) is an important component of air pollution and can
induce lung inflammation and oxidative stress. We hypothesized that PM2. 5 could play a …

PM2. 5‐induced lung inflammation in mice: Differences of inflammatory response in macrophages and type II alveolar cells

M He, T Ichinose, S Yoshida, T Ito, C He… - Journal of Applied …, 2017 - Wiley Online Library
Abstract Particulate matter 2.5 (< PM2. 5 μm) leads to chronic obstructive pulmonary
disease. In this study, biomarkers related to inflammation and oxidative stress in vitro and in …