The role of toll-like receptors 2 and 4 in the pathogenesis of feline pyometra

E Jursza, MP Kowalewski, A Boos, DJ Skarzynski… - Theriogenology, 2015 - Elsevier
Pyometra is the most common uterine disease in queens. To protect itself from infection, the
female reproductive tract possesses several immune mechanisms that are based on …

Oestrous cycle-related changes in production of Toll-like receptors and prostaglandins in the canine endometrium

E Silva, S Henriques, S Brito, G Ferreira-Dias… - Journal of reproductive …, 2012 - Elsevier
The objectives of this study were to evaluate the following events in the canine endometrium
over the course of the oestrous cycle:(i) the transcriptional profiles of genes encoding the …

Identifying diagnostic endocrine markers and changes in endometrial gene expressions during pyometra in cats

E Jursza-Piotrowska, MJ Siemieniuch - Reproductive Biology, 2016 - Elsevier
Pyometra is a significant reproductive problem in cats. The aims of this study were to
evaluate (i) the immunological profile of queens by studying plasma concentrations of …

The Localization of Toll‐like Receptor 2 (TLR 2) in the Endometrium and the Cervix of Dogs at Different Stages of the Oestrous Cycle and with Pyometra

S Chotimanukul… - Reproduction in Domestic …, 2012 - Wiley Online Library
Content The aim of this study was to localize and evaluate the role of T oll‐like receptor 2
(TLR 2) in the endometrium and cervix of bitches at different stages of the oestrous cycle and …

Gene transcription of TLR2, TLR4, LPS ligands and prostaglandin synthesis enzymes are up-regulated in canine uteri with cystic endometrial hyperplasia–pyometra …

E Silva, S Leitão, S Henriques, MP Kowalewski… - Journal of reproductive …, 2010 - Elsevier
Escherichia coli (E. coli) is the most frequent bacterium isolated in cases of cystic
endometrial hyperplasia–pyometra complex, the most frequent endometrial disorder in the …

Differential expression of Toll-like receptor 4 (TLR4) in healthy and infected canine endometrium

S Chotimanukul, S Sirivaidyapong - Theriogenology, 2011 - Elsevier
This study provides the first report into immunohistochemical localization of Toll-like receptor
(TLR) in the canine reproductive tract. TLR4 was investigated in endometrium during the …

LPS‐Challenged TNFα Production, Prostaglandin Secretion, and TNFα/TNFRs Expression in the Endometrium of Domestic Cats in Estrus or Diestrus, and in Cats …

E Jursza, AZ Szóstek, MP Kowalewski… - Mediators of …, 2014 - Wiley Online Library
Progesterone (P4) derivatives which are commonly used to block the cyclicity of domestic
cats disturb the endocrine balance in the endometrium. The aims of this study were (i) to …

Comparison of the effect of lipopolysaccharide on tumor necrosis factor α (TNF-α) secretion and TNF and TNFR1 mRNA levels in feline endometrium throughout the …

E Jursza-Piotrowska, MJ Siemieniuch - Journal of Reproduction and …, 2016 - jstage.jst.go.jp
Endotoxins released by Gram-negative bacteria are potent stimulators of tumor necrosis
factor α (TNF-α) production. The objectives of this study were to evaluate plasma levels of …

Expression of oxytocin, progesterone, and estrogen receptors in the reproductive tract of bitches with pyometra

N Prapaiwan, S Manee-In, E Olanratmanee… - Theriogenology, 2017 - Elsevier
Canine pyometra is considered a serious and life-threatening condition. Due to the
relationship among sex steroid hormones, oxytocin receptor (OTR) expression, and canine …

Expression of Toll-like receptors 2, 4 and 6 in equine endometrial epithelial cells: A comparative in situ and in vitro study

S Schöniger, D Böttcher, T Theuß… - Research in Veterinary …, 2017 - Elsevier
Endometrial epithelial cells form a luminal barrier and are exposed to pathogens and non-
infectious antigens. Toll-like receptors (TLRs) mediate pathogen defenses and tissue …