[HTML][HTML] Proteomics of multiple sclerosis: inherent issues in defining the pathoetiology and identifying (early) biomarkers

MK Sen, MSM Almuslehi, PJ Shortland… - International Journal of …, 2021 - mdpi.com
Multiple Sclerosis (MS) is a demyelinating disease of the human central nervous system
having an unconfirmed pathoetiology. Although animal models are used to mimic the …

Genomic, proteomic, and systems biology approaches in biomarker discovery for multiple sclerosis

CC Huizar, I Raphael, TG Forsthuber - Cellular immunology, 2020 - Elsevier
Multiple sclerosis (MS) is a neuroinflammatory disorder characterized by autoimmune-
mediated inflammatory lesions in CNS leading to myelin damage and axonal loss. MS is a …

Proteomic approaches to decipher mechanisms underlying pathogenesis in multiple sclerosis patients

V Singh, A Tripathi, R Dutta - Proteomics, 2019 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative
disease of the central nervous system (CNS). The cause of MS is unknown, with no effective …

[HTML][HTML] Proteomics in multiple sclerosis: the perspective of the clinician

D Sandi, Z Kokas, T Biernacki, K Bencsik… - International Journal of …, 2022 - mdpi.com
Multiple sclerosis (MS) is the inflammatory demyelinating and neurodegenerative disease of
the central nervous system (CNS) that affects approximately 2.8 million people worldwide. In …

Ten years of proteomics in multiple sclerosis

AS Farias, F Pradella, A Schmitt, LMB Santos… - …, 2014 - Wiley Online Library
Multiple sclerosis, which is the most common cause of chronic neurological disability in
young adults, is an inflammatory, demyelinating, and neurodegenerative disease of the …

Multiple sclerosis biomarker discoveries by proteomics and metabolomics approaches

A Jafari, A Babajani, M Rezaei-Tavirani - Biomarker Insights, 2021 - journals.sagepub.com
Multiple sclerosis (MS) is an autoimmune inflammatory disorder of the central nervous
system (CNS) resulting in demyelination and axonal loss in the brain and spinal cord. The …

Proteomics technologies for biomarker discovery in multiple sclerosis

V Singh, RQ Hintzen, TM Luider, MP Stoop - Journal of neuroimmunology, 2012 - Elsevier
Multiple sclerosis is a disabling inflammatory and neurodegenerative disorder that
predominantly affects young adults. There is a great need for biomarkers, which could …

Comprehensive phenotyping in multiple sclerosis: discovery based proteomics and the current understanding of putative biomarkers

KC O'Connor, SM Roy, CH Becker, DA Hafler… - Disease …, 2006 - content.iospress.com
Currently, there is no single test for multiple sclerosis (MS). Diagnosis is confirmed through
clinical evaluation, abnormalities revealed by magnetic resonance imaging (MRI), and …

[HTML][HTML] Discovery of novel biomarkers for diagnosing and predicting the progression of multiple sclerosis using TMT-based quantitative proteomics

Y Shi, Y Ding, G Li, L Wang, RA Osman, J Sun… - Frontiers in …, 2021 - frontiersin.org
Objective Here, we aimed to identify protein biomarkers that could rapidly and accurately
diagnose multiple sclerosis (MS) using a highly sensitive proteomic immunoassay. Methods …

[HTML][HTML] Molecular biomarkers in multiple sclerosis and its related disorders: A critical review

M Gul, A Azari Jafari, M Shah, S Mirmoeeni… - International journal of …, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous
system (CNS) which can lead to severe disability. Several diseases can mimic the clinical …