There is growing evidence suggesting that vascular pathologies and dysfunction play a
critical role in cognitive impairment, clinical Alzheimer's disease, and dementia. Vascular …

Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …

There is increasing evidence that cerebrovascular dysfunction plays a role not only in
vascular causes of cognitive impairment but also in Alzheimer's disease (AD). Vascular risk …

The prevalence of dementia is increasing in our aging population at an alarming rate.
Because of the heterogeneity of clinical presentation and complexity of disease …

The aging of the central nervous system and the development of incapacitating neurological
diseases like Alzheimer's disease (AD) are generally associated with a wide range of …

Down syndrome (DS) is a common cause of intellectual disability and is also associated with
early age of onset of Alzheimer's disease (AD). Due to an extra copy of chromosome 21 …

Age-related and amyloid-induced pathology of the cerebral microvasculature have been
implicated as potential contributing factors to the pathogenesis of Alzheimer's disease (AD) …

Alzheimer's disease is a progressive brain disorder that gradually destroys a patient's
memory function and ability to carry out daily activities. According to the prevailing amyloid …

Alzheimer's disease (AD) and cerebrovascular disorders are the leading causes of dementia
in our ageing population. Given that the progression of neuropathological changes in the …

Background Vascular contributions to cognitive impairment and dementia (VCID) is a
complex form of dementia, combining aspects of vascular disease and other forms of …