Contextual determinants of TGFβ action in development, immunity and cancer
CJ David, J Massagué - Nature reviews Molecular cell biology, 2018 - nature.com
Few cell signals match the impact of the transforming growth factor-β (TGFβ) family in
metazoan biology. TGFβ cytokines regulate cell fate decisions during development, tissue …
metazoan biology. TGFβ cytokines regulate cell fate decisions during development, tissue …
TGF-β signaling in cell fate control and cancer
Y Yu, XH Feng - Current opinion in cell biology, 2019 - Elsevier
Members of the transforming growth factor-β (TGF-β) family regulate cell fate decisions
during early embryonic development and tissue homeostasis in the adult. Deregulation of …
during early embryonic development and tissue homeostasis in the adult. Deregulation of …
The regulation of TGFβ signal transduction
A Moustakas, CH Heldin - Development, 2009 - journals.biologists.com
Transforming growth factor β (TGFβ) pathways are implicated in metazoan development,
adult homeostasis and disease. TGFβ ligands signal via receptor serine/threonine kinases …
adult homeostasis and disease. TGFβ ligands signal via receptor serine/threonine kinases …
Transforming growth factor-β receptors and Smads: regulatory complexity and functional versatility
EH Budi, D Duan, R Derynck - Trends in cell biology, 2017 - cell.com
Transforming growth factor (TGF)-β family proteins control cell physiology, proliferation, and
growth, and direct cell differentiation, thus playing key roles in normal development and …
growth, and direct cell differentiation, thus playing key roles in normal development and …
The TGFbeta superfamily signaling pathway
A Weiss, L Attisano - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
The transforming growth factor (TGF) beta superfamily of secreted factors is comprised of
over 30 members including Activins, Nodals, Bone Morphogenetic Proteins (BMPs), and …
over 30 members including Activins, Nodals, Bone Morphogenetic Proteins (BMPs), and …
Signaling cross talk between TGF-β/Smad and other signaling pathways
K Luo - Cold Spring Harbor perspectives in biology, 2017 - cshperspectives.cshlp.org
Cytokines of the transforming growth factor β (TGF-β) family, including TGF-βs, bone
morphogenic proteins (BMPs), activins, and Nodal, play crucial roles in embryonic …
morphogenic proteins (BMPs), activins, and Nodal, play crucial roles in embryonic …
TGF-β signal transduction spreading to a wider field: a broad variety of mechanisms for context-dependent effects of TGF-β
H Ikushima, K Miyazono - Cell and tissue research, 2012 - Springer
Transforming growth factor (TGF)-β signaling is involved in almost all major cell behaviors
under physiological and pathological conditions, and its regulatory system has therefore …
under physiological and pathological conditions, and its regulatory system has therefore …
Signal transduction by the TGF-β superfamily
L Attisano, JL Wrana - Science, 2002 - science.org
Transforming growth factor–β (TGF-β) superfamily members regulate a plethora of
developmental processes, and disruption of their activity has been implicated in a variety of …
developmental processes, and disruption of their activity has been implicated in a variety of …
Negative regulation of TGF-β receptor/Smad signal transduction
S Itoh, P ten Dijke - Current opinion in cell biology, 2007 - Elsevier
Members of the transforming growth factor-β (TGF-β) family are highly conserved
multifunctional cell–cell signaling proteins that are of key importance for controlling …
multifunctional cell–cell signaling proteins that are of key importance for controlling …
TGF-b signaling and cancer: structural and functional consequences of mutations in Smads
Transforming growth factor-β (TGF-β) and related cytokines control the development and
homeostasis of many tissues by regulating the expression of genes that determine cell …
homeostasis of many tissues by regulating the expression of genes that determine cell …