Amphiregulin (AREG), which acts as one of the ligands for epidermal receptor growth factor
receptor (EGFR), plays a crucial role in tissue repair, inflammation, and immunity. AREG is …

Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely
expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored …

Amphiregulin (Areg) participates in tissue repair and inflammation regulation. As important
effector cells in inflammation, macrophages can be polarized to classically (M1) or …

We have previously shown that SUM‐149 human breast cancer cells require an
amphiregulin (AREG) autocrine loop for cell proliferation. We also demonstrated that AREG …

Neonates are highly susceptible to microbial infections which is partially attributable to
fundamental phenotypic and functional differences between effector cells of the adult and …

AMPHIREGULIN (AREG) is a multifaceted molecule, which acts not only as an extracellular
ligand for EGF receptor (EGFR), but also as an intracellular signaling molecule. It remains …

The epidermal growth factor receptor ligand Amphiregulin has a well-documented role in the
restoration of tissue homeostasis after injury; however, the mechanism by which …

All members of epidermal growth factor (EGF) family are expressed as transmembrane
precursors on cell surfaces and then proteolytically converted to soluble ligands for EGF …

Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is
expressed in a plethora of cancers. The biological roles of AREG in the regulation of the …

Purpose Tumor initiation and progression rely on cellular proliferation and migration. Many
factors are involved in these processes, including growth factors. Amphiregulin (AREG) is …