Estimating optical parameters of biological tissues with photon-counting micro-CT

W Cong, M Li, X Guo, G Wang - JOSA A, 2022 - opg.optica.org
Wavelength-dependent absorption and scattering properties determine the fluorescence
photon transport in biological tissues and image resolution of optical molecular tomography …

Early-photon fluorescence tomography of a heterogeneous mouse model with the telegraph equation

B Zhang, X Cao, F Liu, X Liu, X Wang, J Bai - Applied optics, 2011 - opg.optica.org
In this study, we investigate the performance of early-photon fluorescence tomography
based on a heterogeneous mouse model. The telegraph equation is used to accurately …

Reconstruction of optical parameters for molecular tomographic imaging

W Cong, X Intes, G Wang - arXiv preprint arXiv:1707.01197, 2017 - arxiv.org
Optical molecular tomographic imaging is to reconstruct the concentration distribution of
photon-molecular probes in a small animal from measured photon fluence rates. The …

Micro-computed tomography-guided, non-equal voxel Monte Carlo method for reconstruction of fluorescence molecular tomography

G Quan, K Wang, X Yang, Y Deng… - Journal of Biomedical …, 2012 - spiedigitallibrary.org
The study of dual-modality technology which combines microcomputed tomography (micro-
CT) and fluorescence molecular tomography (FMT) has become one of the main focuses in …

In vivo time-resolved optical spectroscopy of mice

EE Graves, A Petrovsky, R Weissleder… - Biomedical Topical …, 2002 - opg.optica.org
A time-correlated single photon counting (TCSPC) system has been developed for use with
living specimens as part of a fluorescence-mediated molecular tomography scanner. This …

A review of methods for solving the optical molecular tomography

B Wang, S Li, L Zhang, J Li, Y Zhao, J Yu… - Journal of Applied …, 2023 - pubs.aip.org
As a high-sensitivity and non-invasive technique, optical molecular tomography (OMT) can
locate and visualize tissue quantitatively in three dimensions by collecting surface photons …

Experimental determination of optical properties in turbid medium by TCSPC technique

D Qin, H Zhao, Y Tanikawa… - Optical Tomography and …, 2007 - spiedigitallibrary.org
In this article, we briefly described a time-correlated single photon counting (TCSPC) system
specifically designed for extracting the optical properties in turbid medium. This system was …

Fluorescence-enhanced optical tomography of a large tissue phantom using point illumination geometries

R Roy, A Godavarty… - Journal of Biomedical …, 2006 - spiedigitallibrary.org
We demonstrate fluorescence-enhanced optical imaging of single and multiple fluorescent
targets within a large (∼ 1081 cm 3) phantom using frequency-domain photon migration …

Determination of optical properties in turbid medium based on time-resolved determination

D Qin, Z Ma, F Gao, H Zhao - Fifth International Conference on …, 2007 - spiedigitallibrary.org
In this article, we briefly described a time-correlated single photon counting (TCSPC) system
specifically designed for extracting the optical properties in turbid medium. This system was …

Construction of the Jacobian matrix for fluorescence diffuse optical tomography using a perturbation Monte Carlo method

X Zhang - Multimodal Biomedical Imaging VII, 2012 - spiedigitallibrary.org
Image formation in fluorescence diffuse optical tomography is critically dependent on
construction of the Jacobian matrix. For clinical and preclinical applications, because of the …