Although regenerating gene (Reg) protein is reported to have a trophic effect on gastric
epithelial cells, its involvement in human gastric diseases is not clear. We have recently …

Background & Aims: Regenerating gene (Reg) has been isolated from rat regenerating
pancreatic islets, and Reg protein is mitogenic to islet cells. We have recently shown that …

Reg (regenerating gene product) was originally identified as a growth factor involved in
pancreatic regeneration. During the healing course of gastric erosion, Reg expression is …

Regenerating (reg) gene expression was tested in rat gastrointestinal mucosa to investigate
the role played by this gene in the healing of mucosal lesions. Expression of reg mRNA was …

In 1984, Reg protein was shown to be stimulated during the regeneration of pancreatic
islets. Since then, many Reg-related proteins have been identified in humans and other …

Reg protein has a trophic effect on gastric mucosal cells and pancreatic islets. Recently, the
Reg receptor (Reg-R) has been cloned, and Reg-Reg-R interaction has been reported in …

On the basis of its temporal and spatial pattern of expression during the healing of gastric
ulcers, RegI is implied to be a key growth factor governing the gastric progenitor cell …

The gastric pathogen Helicobacter pylori accelerates the progression to gastric cancer but
the precise mechanisms that mediate carcinogenesis remain unidentified. We now describe …

Background & Aims: Regenerating (Reg) protein has a trophic effect on gastric mucosal
cells. We have shown that Reg gene expression is increased in enterochromaffin-like (ECL) …

A prominent pathological feature of murine autoimmune gastritis is a pronounced mucosal
hypertrophy. Here, we examined factors that may be responsible for inducing this …