Probability of transition to psychosis in individuals at clinical high risk: an updated meta-analysis

GS De Pablo, J Radua, J Pereira, I Bonoldi… - JAMA …, 2021 - jamanetwork.com
Importance Estimating the current likelihood of transitioning from a clinical high risk for
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …

Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk

P Fusar-Poli, I Bonoldi, AR Yung… - Archives of general …, 2012 - jamanetwork.com
Context A substantial proportion of people at clinical high risk of psychosis will develop a
psychotic disorder over time. However, the risk of transition to psychosis varies between …

Clinical outcomes in individuals at clinical high risk of psychosis who do not transition to psychosis: a meta-analysis

GS De Pablo, L Soardo, A Cabras, J Pereira… - Epidemiology and …, 2022 - cambridge.org
Aims The clinical outcomes of individuals at clinical high risk of psychosis (CHR-P) who do
not transition to psychosis are heterogeneous and inconsistently reported. We aimed to …

Predictors of transition in patients with clinical high risk for psychosis: an umbrella review

C Andreou, S Eickhoff, M Heide, R de Bock… - Translational …, 2023 - nature.com
Diagnosis of a clinical high-risk (CHR) state enables timely treatment of individuals at risk for
a psychotic disorder, thereby contributing to improving illness outcomes. However, only a …

The temporal dynamics of transition to psychosis in individuals at clinical high-risk (CHR-P) shows negative prognostic effects of baseline antipsychotic exposure: a …

A Raballo, M Poletti, A Preti - Translational Psychiatry, 2023 - nature.com
Meta-analytic evidence indicates that baseline exposure to antipsychotics (AP) in individuals
at clinical high-risk for psychosis (CHR-P) is associated with an even higher risk of transition …

What causes the onset of psychosis in individuals at clinical high risk? A meta-analysis of risk and protective factors

D Oliver, TJ Reilly, O Baccaredda Boy… - Schizophrenia …, 2020 - academic.oup.com
Twenty percent of individuals at clinical high risk for psychosis (CHR-P) develop the disorder
within 2 years. Extensive research has explored the factors that differentiate those who …

Prevention of psychosis: advances in detection, prognosis, and intervention

P Fusar-Poli, GS De Pablo, CU Correll… - JAMA …, 2020 - jamanetwork.com
Importance Detection, prognosis, and indicated interventions in individuals at clinical high
risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To …

Moving beyond transition outcomes: meta-analysis of remission rates in individuals at high clinical risk for psychosis

AE Simon, S Borgwardt, A Riecher-Rössler… - Psychiatry …, 2013 - Elsevier
Recent evidence suggests that transition risks from initial clinical high risk (CHR) status to
psychosis are decreasing. The role played by remission in this context is mostly unknown …

Prediction of transition to psychosis in patients with a clinical high risk for psychosis: a systematic review of methodology and reporting

E Studerus, A Ramyead… - Psychological medicine, 2017 - cambridge.org
BackgroundTo enhance indicated prevention in patients with a clinical high risk (CHR) for
psychosis, recent research efforts have been increasingly directed towards estimating the …

Prognostic accuracy and clinical utility of psychometric instruments for individuals at clinical high-risk of psychosis: a systematic review and meta-analysis

D Oliver, M Arribas, J Radua, G Salazar de Pablo… - Molecular …, 2022 - nature.com
Accurate prognostication of individuals at clinical high-risk for psychosis (CHR-P) is an
essential initial step for effective primary indicated prevention. We aimed to summarise the …