The session kicked off with Shen's lecture “Uncovering the genetic basis of Parkinson's
disease worldwide.” He started his talk by showing clinical vignettes of multiethnic …

Abstract Background About 5–10% of Parkinson's disease (PD) cases are early onset
(EOPD), with several genes implicated, including GBA1, PRKN, PINK1, and SNCA. The …

Rapidly advancing sequencing technologies offer new and cost-effective approaches to
identify patients with hereditary neurological diseases. While studying small numbers of …

Over the past several decades, common and rare variants in multiple genes have been
associated with Parkinson's disease (PD). PD is a neurodegenerative disorder primarily …

Background: Although seven genes (LRRK2, GBA1, PRKN, PINK1, SNCA, PARK7 and
VPS35) are established as causative for PD, people with PD (PwP) are often unaware of …

Apart from the GWAS risk loci, variants in the GBA1 gene are the most common risk factor
known to date to develop Parkinson's disease (PD). 1, 2 Genetic testing and-counseling of …

Observational studies in Parkinson's disease (PD) deeply characterize relatively small
numbers of participants. The Molecular Integration in Neurological Diagnosis Initiative seeks …

Editorial Sherer, Frasier, Langston & Fiske crude categories over time, making it difficult to
link such clinical distinctions to underlying biological differences [4]. Specific variants in …

Parkinson's disease (PD) is the fastest growing neurological disorder worldwide, taking into
account age-standardized rates for prevalence, disability and deaths (1). PD is …

Through a targeted recruitment 23andMe has collected DNA and patient-reported symptoms
from more than 10,000 subjects reporting a physician-verified diagnosis of PD. This study …