Hypoxia, especially altitude associated hypoxia is known to cause severe physiological
alterations and life-threatening conditions. Impaired redox balance along with oxidative …

Hypoxia-induced responses are frequently encountered during cardiovascular injuries.
Hypoxia triggers intracellular reactive oxygen species/nitric oxide (NO) imbalance. Recent …

Nitric oxide (NO•) from inducible NO• synthase (iNOS) has been reported to either protect
against, or contribute to, hypoxia/re-oxygenation lung injury. The present work aimed to …

Nitrogen oxides are endogenously produced signaling/effector molecules that have the
potential to both cause and ameliorate oxidative stress. Whether nitrogen oxides behave as …

PURPOSE: The present study analyzes the role of the nitric oxide (NO) derived from
inducible NO synthase (iNOS) under cardiac hypoxia/reoxygenation situations. METHODS …

Nitric oxide (NO) is a highly reactive molecule that rapidly diffuses and permeates cell
membranes. In animals, NO is implicated in a number of diverse physiological processes …

Aim Hypoxia is an important feature of multiple diseases like cancer and obesity and also an
environmental stressor to high altitude travelers. Emerging research suggests the …

Many cellular functions in physiology are regulated by the direct interaction of NO with target
biomolecules. In many pathophysiologic and toxicologic mechanisms, NO first reacts with …

Hypoxia is an often seen problem resulting from conditions such as ischemia, hemorrhage,
stroke, premature birth, and other cardiovascular difficulties. To find useful remedies that are …

The S-nitrosoglutathione-metabolizing enzyme, GSNO reductase (GSNOR), has emerged
as an important regulator of protein S-nitrosylation. GSNOR ablation is protective in models …