[图书][B] Invertebrate Models of Natural and Drug‐Sensitive Reward

R Huber, M van Staaden - 2019 - books.google.com
The rewarding properties of drugs depend on their capacity to activate appetitive
motivational states. Because the mechanisms underlying natural reward are an important …

[HTML][HTML] invertebrate models of natural and drug-sensitive reward

M van Staaden, R Huber - Frontiers in Physiology, 2019 - frontiersin.org
The relationship between insects and humans is a complex one, characterized biotically as
commensalism, mutualism, or parasitism. This collection of papers reveals yet another …

Drug-sensitive reward in crayfish: An invertebrate model system for the study of SEEKING, reward, addiction, and withdrawal

R Huber, JB Panksepp, T Nathaniel, A Alcaro… - Neuroscience & …, 2011 - Elsevier
In mammals, rewarding properties of drugs depend on their capacity to activate appetitive
motivational states. With the underlying mechanisms strongly conserved in evolution …

The rewarding properties of methamphetamine in an invertebrate model of drug addiction

A Imeh-Nathaniel, A Adedeji, R Huber… - Physiology & behavior, 2016 - Elsevier
The rewarding properties of drugs in the mammalian system depend on their ability to
activate appetitive motivational states. The associated underlying mechanism is strongly …

Drug-sensitive reward in crayfish: exploring the neural basis of addiction with automated learning paradigms

R Huber, A Imeh-Nathaniel, TI Nathaniel, S Gore… - Behavioural …, 2018 - Elsevier
Results of recent work from our labs and those of others have broadened perspectives on
addiction beyond a human-specific, cognitive phenomenon. Addictive plant alkaloids are …

Crayfish learning: addiction and the ganglionic brain

MJ van Staaden, R Huber - Perspectives on Behavior Science, 2018 - Springer
Recognizing addiction as a phenomenon with deep evolutionary roots grants valuable new
perspectives into understanding its behavioral features, as well as its underlying neural …

[HTML][HTML] Crayfish self-administer amphetamine in a spatially contingent task

U Datta, M Van Staaden, R Huber - Frontiers in Physiology, 2018 - frontiersin.org
Natural reward is an essential element of any organism's ability to adapt to environmental
variation. Its underlying circuits and mechanisms guide the learning process as they help …

[HTML][HTML] The sensitivity of the crayfish reward system to mammalian drugs of abuse

AT Shipley, A Imeh-Nathaniel, VB Orfanakos… - Frontiers in …, 2017 - frontiersin.org
The idea that addiction occurs when the brain is not able to differentiate whether specific
reward circuits were triggered by adaptive natural rewards or falsely activated by addictive …

[引用][C] Commentary: animal models/tests of drug addiction: a quest for the holy grail, or the pursuit of wild geese?

DN Stephens - Addiction Biology, 2006 - Wiley Online Library
The review by Sanchis-Segura & Spanagel (2006) provides a useful overview of the
theoretical background behind some of the methods used by animal researchers into drug …

The neuroscience of natural rewards: relevance to addictive drugs

AE Kelley, KC Berridge - Journal of neuroscience, 2002 - Soc Neuroscience
Addictive drugs act on brain reward systems, although the brain evolved to respond not to
drugs but to natural rewards, such as food and sex. Appropriate responses to natural …