In situ fabrication of nerve growth factor encapsulated chitosan nanoparticles in oxidized bacterial nanocellulose for rat sciatic nerve regeneration

Z Wei, FF Hong, Z Cao, SY Zhao, L Chen - Biomacromolecules, 2021 - ACS Publications
Autograft is currently the gold standard in the clinical treatment of peripheral nerve injury
(PNI), which, however, is limited by the availability of a donor nerve and secondary injuries …

[PDF][PDF] Development of a bioactive scaffold based on NGF containing PCL/chitosan nanofibers for nerve regeneration

H Afrash, N Nazeri, P Davoudi… - … Res. Appl. Chem, 2021 - biointerfaceresearch.com
Nanofibers are used in a wide range of applications, including scaffolds for tissue
engineering. Electrospinning is a promising technique to fabricate nanofibrous scaffolds …

Nerve regeneration effect of a composite bioactive carboxymethyl chitosan-based nerve conduit with a radial texture

Y Zhang, Z Jiang, Y Wang, L Xia, S Yu, H Li, W Zhang… - Molecules, 2022 - mdpi.com
Chitosan (CTS) has been used as a nerve guidance conduit (NGC) material for bridging
peripheral nerve defects due to its biocompatible, biodegradable, and non-toxic properties …

Chitosan-based nerve guidance conduit with microchannels and nanofibers promotes schwann cells migration and neurite growth

G Zhou, Y Chen, F Dai, X Yu - Colloids and Surfaces B: Biointerfaces, 2023 - Elsevier
Peripheral nerve injury (PNI) is the leading cause of permanent dysfunction in movement
and sensation. Despite the rapid development of tissue engineering in peripheral nerve …

Chitosan nerve conduit filled with ZIF-8-functionalized guide microfibres enhances nerve regeneration and sensory function recovery in sciatic nerve defects

X Zhang, T Qi, Y Sun, X Chen, P Yang, S Wei… - Chemical Engineering …, 2024 - Elsevier
Nerve conduits have shown promise as alternatives to autologous nerves, but their repair
effects need to be improved. The topographical guidance and functionalization of scaffolds …

Enhanced sciatic nerve regeneration by poly-L-lactic acid/multi-wall carbon nanotube neural guidance conduit containing Schwann cells and curcumin encapsulated …

HK Jahromi, A Farzin, E Hasanzadeh… - Materials Science and …, 2020 - Elsevier
The main aim of this study was to improve the efficacy of peripheral nerve regeneration by
an artificial neural guidance conduit (NGC) as a carrier to transplant allogeneic Schwann …

Preparation of NGF encapsulated chitosan nanoparticles and its evaluation on neuronal differentiation potentiality of canine mesenchymal stem cells

B Mili, K Das, A Kumar, AC Saxena, P Singh… - Journal of Materials …, 2018 - Springer
Sustained and controlled release of neurotrophic factors in target tissue through
nanomaterial based delivery system could be a better strategy for nerve tissue regeneration …

Biocompatible chitin hydrogel incorporated with PEDOT nanoparticles for peripheral nerve repair

L Huang, X Yang, L Deng, D Ying, A Lu… - … Applied Materials & …, 2021 - ACS Publications
The nerve guidance conduit (NGC) is a promising clinical strategy for regenerating the
critical-sized peripheral nerve injury. In this study, the polysaccharide chitin is used to …

Incorporation of chitosan microspheres into collagen-chitosan scaffolds for the controlled release of nerve growth factor

W Zeng, M Rong, X Hu, W Xiao, F Qi, J Huang, Z Luo - PloS one, 2014 - journals.plos.org
Background Artifical nerve scaffold can be used as a promising alternative to autologous
nerve grafts to enhance the repair of peripheral nerve defects. However, current nerve …

[HTML][HTML] Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotrophic factor and vascular endothelial growth factor repair …

F Rao, Y Wang, D Zhang, C Lu, Z Cao, J Sui, M Wu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Autologous nerve transplantation, which is the gold standard for clinical treatment of
peripheral nerve injury, still has many limitations. In this study, aligned chitosan fiber …