Measures of B6 status are categorized as direct biomarkers and as functional biomarkers.
Direct biomarkers measure B6 vitamers in plasma/serum, urine and erythrocytes, and …

Pyridoxal 5'-phosphate (PLP) is a cofactor for enzymes catalyzing transami nase,
decarboxylase, and synthetase reactions (among others) in pathways spanning …

This report on vitamin B-12 (B12) is part of the Biomarkers of Nutrition for Development
(BOND) Project, which provides state-of-the art information and advice on the selection, use …

Background: Tryptophan metabolism through the kynurenine pathway includes 2 vitamin B-
6 [pyridoxal 5′-phosphate (PLP)]–dependent enzymes. We recently showed that plasma 3 …

The EAT-Lancet commission recently suggested that transformation to healthy diets by 2050
will require a reduction of at least 50% in consumption of foods such as red meat and sugar …

Background: Homocysteine, a risk factor of cardiovascular disease, cognitive disorders, and
pregnancy complications, exists at a point of metabolic convergence of several B vitamins …

The post-genomic era has been driven by the development of technologies that allow the
function of cells and whole organisms to be explored at the molecular level. Metabolomics is …

The metabo-ring initiative brought together five nuclear magnetic resonance instruments
(NMR) and 11 different mass spectrometers with the objective of assessing the reliability of …

The active form of vitamin B6, pyridoxal 5′-phosphate (PLP), serves as a co-factor in more
than 150 enzymatic reactions. Plasma PLP has consistently been shown to be low in …

Current understanding of vitamin D tends to be focussed on the measurement of the major
circulating form 25‐hydroxyvitamin D3 (25OHD3) and its conversion to the active hormonal …