Platinum-based anticancer agents such as cisplatin and its analogues are widely used for
treating multiple cancers. However, due to the inferior water-solubility, chemoresistance and …

Background Breast cancer is the leading cause of cancer death in women. Chemotherapy to
inhibit the proliferation of cancer cells is considered to be the most important therapeutic …

In this report, a newly liposomal formulation of paclitaxel (PTX) based on dual paclitaxel
succinate glycerophosphorylcholine (Di-PTX-GPC) prodrug was developed. The Di-PTX …

In this study, we designed and developed a novel asialoglycoprotein receptor (ASGPR)-
targeted PEGylated paclitaxel (PTX) nanoliposome for hepatocellular carcinoma (HCC). N …

Cisplatin is a platinum-based chemotherapeutic agent widely used in the treatment of
various solid tumors. However, a major challenge in the use of cisplatin and in the …

Platinum-based chemotherapy, such as cisplatin, oxaliplatin, and carboplatin, is one of the
most widely utilized classes of cancer therapeutics. While highly effective, the clinical …

To find out potent paclitaxel (PTX) formulations for cancer chemotherapy, we formulated PTX
in O/W emulsion and liposome selected as candidates of nanocarriers for PTX. Surface …

Codelivery of two or multiple chemotherapeutics for enhanced anticancer efficacy is a
commonly used strategy in cancer treatment, but the essential antagonistic performance of …

Low levels of accumulation and permeability in tumors are two primary reasons for the
limited efficacy of conventional antineoplastic nanodrugs. In the present study, based on an …

This study aimed to develop novel temperature-sensitive liposomes loading paclitaxel (PTX-
TSL) and evaluate them in vitro to improve the delivery efficiency and targeting of PTX. K237 …