[HTML][HTML] Bone marrow mononuclear cells for joint therapy: the role of macrophages in inflammation resolution and tissue repair
BC Menarim, JN MacLeod… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is the most prevalent joint disease causing major disability and medical
expenditures. Synovitis is a central feature of OA and is primarily driven by macrophages …
expenditures. Synovitis is a central feature of OA and is primarily driven by macrophages …
[HTML][HTML] Mesenchymal stem cell-based therapy of osteoarthritis: Current knowledge and future perspectives
CR Harrell, BS Markovic, C Fellabaum… - Biomedicine & …, 2019 - Elsevier
Osteoarthritis (OA) is a chronic, prevalent, debilitating joint disease characterized by
progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions …
progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions …
[HTML][HTML] Mesenchymal stem cells: Current concepts in the management of inflammation in osteoarthritis
Osteoarthritis (OA) has traditionally been known as a “wear and tear” disease, which is
mainly characterized by the degradation of articular cartilage and changes in the …
mainly characterized by the degradation of articular cartilage and changes in the …
[HTML][HTML] Revolutionizing osteoarthritis treatment: How mesenchymal stem cells hold the key
R Tian, S Su, Y Yu, S Liang, C Ma, Y Jiao… - Biomedicine & …, 2024 - Elsevier
Osteoarthritis (OA) is a multifaceted disease characterized by imbalances in extracellular
matrix metabolism, chondrocyte and synoviocyte senescence, as well as inflammatory …
matrix metabolism, chondrocyte and synoviocyte senescence, as well as inflammatory …
[HTML][HTML] Cell-based therapies have disease-modifying effects on osteoarthritis in animal models. A systematic review by the ESSKA Orthobiologic Initiative. Part 2 …
A Boffa, C Perucca Orfei, Y Sourugeon, L Laver… - Knee Surgery, Sports …, 2023 - Springer
Purpose Aim of this systematic review was to determine if bone marrow-derived cell-based
injectable therapies induce disease-modifying effects in joints affected by osteoarthritis (OA) …
injectable therapies induce disease-modifying effects in joints affected by osteoarthritis (OA) …
[HTML][HTML] Pro-regenerative dialogue between macrophages and mesenchymal stem/stromal cells in osteoarthritis
C Bohaud, R Contreras-Lopez, J De La Cruz… - Frontiers in Cell and …, 2021 - frontiersin.org
Osteoarthritis (OA), the most common degenerative and inflammatory joint disorder, is
multifaceted. Indeed, OA characteristics include cartilage degradation, osteophytes …
multifaceted. Indeed, OA characteristics include cartilage degradation, osteophytes …
The challenge and the promise of bone marrow cells for human cartilage repair
CR Chu - Cartilage, 2015 - journals.sagepub.com
The cartilage repair potential of bone marrow–derived stem cells has been well described.
Harnessing this potential for human articular cartilage repair remains challenging …
Harnessing this potential for human articular cartilage repair remains challenging …
[HTML][HTML] Mesenchymal stem cells in osteoarthritis therapy: a review
C Zhu, W Wu, X Qu - American journal of translational research, 2021 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a chronic joint disease that generally occurs worldwide with pain and
disability. The progression is slow, and it is mostly diagnosed midlife and often disturbs the …
disability. The progression is slow, and it is mostly diagnosed midlife and often disturbs the …
[HTML][HTML] Advances in mesenchymal stem cell therapy for osteoarthritis: from preclinical and clinical perspectives
Z Lv, X Cai, Y Bian, Z Wei, W Zhu, X Zhao, X Weng - Bioengineering, 2023 - mdpi.com
The prevalence of osteoarthritis (OA), a degenerative disorder of joints, has substantially
increased in recent years. Its key pathogenic hallmarks include articular cartilage …
increased in recent years. Its key pathogenic hallmarks include articular cartilage …
Mesenchymal stem cell therapy for osteoarthritis: current perspectives
Osteoarthritis (OA) is a painful chronic condition with a significant impact on quality of life.
The societal burden imposed by OA is increasing in parallel with the aging population; …
The societal burden imposed by OA is increasing in parallel with the aging population; …
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