Developing amorphous solid dispersions with good flow properties is always challenging for
formulation scientists to convert into tablets. Hence, the present study investigates the impact …

Solid dispersion (SD) technique is a promising strategy to improve the solubility and
dissolution of BCS class II drugs. However, only few products are marketed till today based …

Orodispersible or Mouth dissolving tablets are those when put on tongue, disintegrates
instantaneously, releasing the drug, which dissolves or disperses in the saliva. The faster …

Objective: The aim of this work was to investigate the potential of controlled precipitation of
flurbiprofen on solid surface, in the presence or absence of hydrophilic polymers, as a tool …

Aim: The intent of present study is to formulate fast dissolving tablets of flurbiprofen using
different superdisintegrants to improve the dissolution and bioavailability. Place and …

We aimed to develop an immediate-release flurbiprofen (FLU) and esomeprazole (ESO)
combination formulation with enhanced gastric aqueous solubility and dissolution rate …

To develop a novel flurbiprofen-loaded solid dispersion without crystalline change, various
flurbiprofen-loaded solid dispersions were prepared with water, sodium carboxylmethyl …

The aim of the present study was to develop and evaluate a novel drug solubilization
platform (so-called solid nanodispersion) prepared by a simple co-grinding and solvent-free …

Sildenafil citrate undergoes first-pass metabolism, resulting in poor oral bioavailability at 25–
41% of the administered dose. This study aimed to design and optimize fast-disintegrating …

Solubility limited bioavailability is one of the crucial parameters that affect the formulation
development of the new chemical entities. Thus the major constraint in the pharmaceutical …