We have previously shown that C57BL/6J (B6) mice develop severe obesity and diabetes if
weaned onto high-fat diets, whereas A/J mice tend to be obesity and diabetes-resistant. The …

We have previously shown that the C57BL/6J (B6) mouse will develop obesity and diabetes
if raised on a high-fat diet. Because high fat feeding is associated with hyperphagia, the …

We have previously demonstrated that the C57BL/6J (B 6J) mouse will develop severe
obesity, hyperglycemia, and hyperinsulinemia if weaned onto a high-fat, high-sucrose (HH) …

We investigated the effects of diet-induced obesity on glucose metabolism in two strains of
mice, C57BL/6J and A/J. Twenty animals from each strain received ad libitum exposure to a …

C57BL/6J (B6) and AKR/J (AKR) inbred strains of mice develop a comparable degree of
obesity when fed a high-fat diet. However, although obese B6 mice are more glucose …

To understand features of human obesity and type 2 diabetes mellitus (T2D) that can be
recapitulated in the mouse, we compared C57BL/6J mice fed a Western‐style diet (WD) to …

Previous research in our laboratory has demonstrated that the C57BL/6J (B/6J) mouse has a
predisposition to develop severe obesity if placed on a high-fat diet. In the present study we …

Objective: The aim of this study was to assess the suitability of A/J and C57BL/6J mice of
both sexes as models of some components of the human metabolic syndrome (MetS) under …

C57BL/6J mice were fed a high-fat, carbohydrate-free diet (HFD) for 9 mo. Approximately
50% of the mice became obese and diabetic (ObD),∼ 10% lean and diabetic (LD),∼ 10 …

Obesity is a strong risk factor for the development of type 2 diabetes. We have previously
reported that in adipose tissue of obese (ob/ob) mice, the expression of adipogenic genes is …