Abstract Treatment of cardiac disease in patients with dystrophinopathies substantially
improves outcomes. In this Review, we summarize and discuss findings from the past 20 …

Dystrophinopathies are a group of distinct neuromuscular diseases that result from
mutations in the structural cytoskeletal Dystrophin gene. Dystrophinopathies include …

The importance of cardiomyopathy to the clinical course of the dystrophinopathies varies
according to the nature of the dystrophin defect. In Becker muscular dystrophy (BMD) …

Dystrophinopathies are due to mutations in the dystrophin gene on chromosome Xp21. 1
and comprise the allelic entities Duchenne muscular dystrophy (DMD), Becker muscular …

Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive condition caused
primarily by out-of-frame mutations in the dystrophin gene. In males, DMD presents with …

Duchenne's muscular dystrophy is an X-linked neuromuscular disease that manifests as
muscle atrophy and cardiomyopathy in young boys. However, a considerable percentage of …

Cardiomyopathy is a frequent occurrence in muscular dystrophy, and heart disease in
muscular dystrophy can contribute to both morbidity and mortality. A number of novel …

Aims Dilated cardiomyopathy (DCM) associated with dystrophin gene (DMD) mutations in
individuals with mild or absent skeletal myopathy is often indistinguishable from other DCM …

Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), and X-linked
dilated cardiomyopathy (XL-DCM) consist of a unique clinical entity, the dystrophinopathies …

Cardiac dysfunction is a frequent manifestation of Duchenne muscular dystrophy (DMD) and
a common cause of death for individuals with this condition. Early diastolic dysfunction and …