The creation of versatile platforms for developing dual‐channel near‐infrared fluorescent
(NIRF) and photoacoustic (PA) probes, especially those engineered to minimize channel …

Inflammation is associated with many diseases, so the development of an excellent near
infrared fluorescent (NIRF) and photoacoustic (PA) dual-modality probe is crucial for the …

Herein, we describe an energy balance strategy between fluorescence and photoacoustic
effects by sulfur substitution to transform existing hemicyanine dyes (Cy) into optimized …

Shortwave infrared (SWIR) dyes are characterized by their ability to absorb light from 900 to
1400 nm, which is ideal for deep tissue imaging owing to minimized light scattering and …

Small-molecule based multifunctional probes play significant roles in biomedical science
and possess high clinical translational ability. However, the preparation of these promising …

Fluorescence imaging in the second near-infrared window (NIR-II) has been an emerging
technique in diverse in vivo applications with high sensitivity/resolution and deep tissue …

In this chapter, we introduce a two-phase tuning approach for developing highly sensitive
photoacoustic probes for imaging nitric oxide (NO) in the near-infrared (NIR)-II window. Due …

Photoacoustic (PA) imaging is an emerging molecular imaging modality that complements
fluorescence imaging and enables high resolution within deep tissue. Fluorescence/PA …

Ratiometric near-infrared fluorescent pH probes with various pKa values were innovatively
designed and synthesized based on cyanine with a diamine moiety. The photochemical …

Abstract Near‐infrared fluorescence (NIRF)/photoacoustic (PA) dual‐modality imaging
integrated high‐sensitivity fluorescence imaging with deep‐penetration PA imaging has …