Heart failure is typically caused by different cardiovascular conditions and has a poor
prognosis. Despite the advances in treatment in recent decades, heart failure has remained …

Macrophages are essential components of the immune system and play a role in the normal
functioning of the cardiovascular system. Depending on their origin and phenotype, cardiac …

Despite mounting evidence implicating inflammation in cardiovascular diseases, attempts at
clinical translation have shown mixed results. Recent preclinical studies have reenergized …

Cardiomyopathy is an important cause of heart failure, causing systolic and diastolic
dysfunction and promoting adverse cardiac remodeling. Macrophages, as important immune …

The important contribution of monocytes and macrophages to cardiovascular disease and
heart failure pathophysiology has attracted significant attention in the past several years …

Cardiac hypertrophy, initiated by a variety of physiological or pathological stimuli
(hemodynamic or hormonal stimulation or infarction), is a critical early adaptive …

Adverse cardiac remodeling after acute myocardial infarction is the most important
pathological mechanism of heart failure, and still a major problem in clinical practice …

Understanding tissue macrophage biology has become challenging in recent years due the
ever-increasing complexity in macrophage-subset identification and functional …

Early and prompt reperfusion therapy has markedly improved the survival rates among
patients enduring myocardial infarction (MI). Nonetheless, the resulting adverse remodeling …

Although great advances have been made, the problem of irreversible myocardium loss due
to the limited regeneration capacity of cardiomyocytes has not been fully solved. The …