Global issues in allergy and immunology: parasitic infections and allergy

AA Cruz, PJ Cooper, CA Figueiredo… - Journal of Allergy and …, 2017 - Elsevier
Allergic diseases are on the increase globally in parallel with a decrease in parasitic
infection. The inverse association between parasitic infections and allergy at an ecological …

Chronic helminth infections modulate allergen‐specific immune responses: protection against development of allergic disorders?

HH Smits, M Yazdanbakhsh - Annals of medicine, 2007 - Taylor & Francis
Inflammatory diseases are on the rise in westernized countries, but also in urbanized areas
of developing countries. A number of studies have now demonstrated a negative association …

[HTML][HTML] Parasitic helminth infections and the control of human allergic and autoimmune disorders

RM Maizels - Clinical Microbiology and Infection, 2016 - Elsevier
The profile of global health today presents a striking reciprocal distribution between parasitic
diseases in many of the world's lower-income countries, and ever-increasing levels of …

[HTML][HTML] Human helminths and allergic disease: the hygiene hypothesis and beyond

HC Santiago, TB Nutman - The American journal of tropical …, 2016 - ncbi.nlm.nih.gov
There is much debate about the interaction between helminths and allergic disease. The
“Hygiene Hypothesis,” a very popular concept among scientists and the lay public, states …

Interactions between helminth parasites and allergy

PJ Cooper - Current opinion in allergy and clinical immunology, 2009 - journals.lww.com
Interactions between helminth parasites and allergy : Current Opinion in Allergy and Clinical
Immunology Interactions between helminth parasites and allergy : Current Opinion in Allergy …

Parasites and allergy: Observations from Africa

H Mpairwe, AS Amoah - Parasite immunology, 2019 - Wiley Online Library
Population studies from the African continent have observed a marked increase in the
prevalence of allergy‐related diseases over the past few decades, but the cause of this rise …

Worms as therapeutic agents for allergy and asthma: understanding why benefits in animal studies have not translated into clinical success

H Evans, E Mitre - Journal of Allergy and Clinical Immunology, 2015 - Elsevier
Helminth infections are associated with decreased rates of autoimmunity and allergy, and
several clinical studies have demonstrated that intentional infection with helminths can …

Suppression of TH2-type allergic reactions by helminth infection

PG Fallon, NE Mangan - Nature Reviews Immunology, 2007 - nature.com
There is no immunological mechanism to adequately explain the sudden epidemic in
allergies noted in the last 30 years in developed countries. The reduction in the …

What can parasites tell us about the pathogenesis and treatment of asthma and allergic diseases

S Bohnacker, F Troisi, M de los Reyes Jiménez… - Frontiers in …, 2020 - frontiersin.org
The same mechanisms that enable host defense against helminths also drive allergic
inflammation. This suggests that pathomechanisms of allergic diseases represent …

Parasitic worm therapy for allergy: Is this incongruous or avant‐garde medicine?

DI Pritchard, DG Blount… - Clinical & …, 2012 - Wiley Online Library
Helminth (worm) therapy has already been used in clinical trials associated with allergy.
These were generally small scale, safety orientated trials of short duration, justified by …