The absence of the Duffy protein at the surface of erythrocytes was considered for decades
to confer full protection against Plasmodium vivax as this blood group is the receptor for the …

Plasmodium vivax has been largely neglected over the past century, despite a widespread
recognition of its burden across region where it is endemic. The parasite invades …

The ability of the malaria parasite Plasmodium vivax to invade erythrocytes is dependent on
the expression of the Duffy blood group antigen on erythrocytes. Consequently, Africans …

Background Plasmodium vivax shows a small prevalence in West and Central Africa due to
the high prevalence of Duffy negative people. However, Duffy negative individuals infected …

Duffy blood group antigen (Duffy antigen/receptor for chemokines, atypical chemokine
receptor-1, Duffy antigen), an essential Plasmodium vivax invasion receptor, is absent in …

Background Plasmodium vivax invasion requires interaction between the human Duffy
antigen on the surface of erythrocytes and the P. vivax Duffy binding protein (PvDBP) …

The erythrocyte silent Duffy blood group phenotype in Africans is thought to confer
resistance to Plasmodium vivax blood-stage infection. However, recent studies report P …

Plasmodium vivax, a major agent of malaria in both temperate and tropical climates, has
been thought to be unable to infect humans lacking the Duffy (Fy) blood group antigen …

Malaria therapy, experimental, and epidemiological studies have shown that erythrocyte
Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte …

The Duffy blood group is a critical receptor for Plasmodium vivax (P. vivax) invasion of red
blood cells, and consequently, P. vivax infections were considered rare in sub-Saharan …