Liquid biopsy for monitoring of tumor dormancy and early detection of disease recurrence in solid tumors

I Heidrich, B Deitert, S Werner, K Pantel - Cancer and Metastasis Reviews, 2023 - Springer
Cancer is one of the three leading causes of death worldwide. Even after successful therapy
and achieving remission, the risk of relapse often remains. In this context, dormant residual …

[HTML][HTML] Liquid biopsies, what we do not know (yet)

A Bardelli, K Pantel - Cancer cell, 2017 - cell.com
The inherent molecular heterogeneity of metastatic tumors and the ability of cancer
genomes to dynamically evolve are not properly captured by tissue specimens. Analysis of …

The potential of liquid biopsies for the early detection of cancer

E Heitzer, S Perakis, JB Geigl, MR Speicher - NPJ precision oncology, 2017 - nature.com
Precision medicine refers to the choosing of targeted therapies based on genetic data. Due
to the increasing availability of data from large-scale tumor genome sequencing projects …

Liquid biopsy to detect minimal residual disease: methodology and impact

N Honoré, R Galot, C van Marcke, N Limaye… - Cancers, 2021 - mdpi.com
Simple Summary The field of liquid biopsy is rapidly evolving. Techniques that improve
accuracy are constantly being developed, and clinicians increasingly use liquid biopsy as a …

The metastatic cascade as the basis for liquid biopsy development

Z Eslami-S, LE Cortés-Hernández… - Frontiers in …, 2020 - frontiersin.org
The metastatic cascade describes the process whereby aggressive cancer cells leave the
primary tumor, travel through the bloodstream, and eventually reach distant organs to …

Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

SN Lone, S Nisar, T Masoodi, M Singh, A Rizwan… - Molecular cancer, 2022 - Springer
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …

Clinical and biological aspects of disseminated tumor cells and dormancy in breast cancer

A Ring, M Spataro, A Wicki, N Aceto - Frontiers in Cell and …, 2022 - frontiersin.org
Progress in detection and treatment have drastically improved survival for early breast
cancer patients. However, distant recurrence causes high mortality and is typically …

Liquid biopsy and tumor heterogeneity in metastatic solid tumors: the potentiality of blood samples

M Russano, A Napolitano, G Ribelli, M Iuliani… - Journal of Experimental …, 2020 - Springer
In a large number of cancer types, treatment selection depends on the presence of specific
tumor biomarkers. Due to the dynamic nature of cancer, very often these predictive …

[HTML][HTML] The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring

SM Batool, A Yekula, P Khanna, T Hsia… - Cell Reports …, 2023 - cell.com
The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for
cancer and other diseases. Liquid biopsy allows minimally invasive molecular …

Liquid biopsy-based biomarkers of treatment response and resistance

E Kilgour, DG Rothwell, G Brady, C Dive - Cancer cell, 2020 - cell.com
Predictive biomarkers aid selection of personalized therapy targeted to molecular alterations
within an individual's tumor. Patients' responses to targeted therapies are commonly …