Percentage of heavy drinking days following psilocybin-assisted psychotherapy vs placebo in the treatment of adult patients with alcohol use disorder: a randomized …
MP Bogenschutz, S Ross, S Bhatt, T Baron… - JAMA …, 2022 - jamanetwork.com
Importance Although classic psychedelic medications have shown promise in the treatment
of alcohol use disorder (AUD), the efficacy of psilocybin remains unknown. Objective To …
of alcohol use disorder (AUD), the efficacy of psilocybin remains unknown. Objective To …
Psilocybin-assisted treatment for alcohol dependence: a proof-of-concept study
MP Bogenschutz, AA Forcehimes… - Journal of …, 2015 - journals.sagepub.com
Several lines of evidence suggest that classic (5HT2A agonist) hallucinogens have clinically
relevant effects in alcohol and drug addiction. Although recent studies have investigated the …
relevant effects in alcohol and drug addiction. Although recent studies have investigated the …
[HTML][HTML] Therapeutic effect of psilocybin in addiction: A systematic review
PB van der Meer, JJ Fuentes, AA Kaptein… - Frontiers in …, 2023 - frontiersin.org
Background Psychedelic-assisted therapy [eg, with lysergic acid diethylamide (LSD)] has
shown promising results as treatment for substance use disorders (SUDs). Previous …
shown promising results as treatment for substance use disorders (SUDs). Previous …
Psilocybin history, action and reaction: a narrative clinical review
Hallucinogenic mushrooms have been used in religious and cultural ceremonies for
centuries. Of late, psilocybin, the psychoactive compound in hallucinogenic mushrooms, has …
centuries. Of late, psilocybin, the psychoactive compound in hallucinogenic mushrooms, has …
[HTML][HTML] Clinical interpretations of patient experience in a trial of psilocybin-assisted psychotherapy for alcohol use disorder
MP Bogenschutz, SK Podrebarac, JH Duane… - Frontiers in …, 2018 - frontiersin.org
After a hiatus of some 40 years, clinical research has resumed on the use of classic
hallucinogens to treat addiction. Following completion of a small open-label feasibility study …
hallucinogens to treat addiction. Following completion of a small open-label feasibility study …
Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse
MW Meinhardt, C Güngör, I Skorodumov… - …, 2020 - nature.com
For most psychiatric disorders, including alcohol use disorder (AUD), approved
pharmacological treatments are limited in their effectiveness, and new drugs that can easily …
pharmacological treatments are limited in their effectiveness, and new drugs that can easily …
Classic psychedelics in the treatment of substance use disorder: potential synergies with twelve-step programs
DB Yaden, AP Berghella, PS Regier… - International Journal of …, 2021 - Elsevier
Several pilot studies have provided evidence supporting the potential of classic
psychedelics like psilocybin in the treatment of substance use disorders (SUDs). If larger …
psychedelics like psilocybin in the treatment of substance use disorders (SUDs). If larger …
[HTML][HTML] The psychedelic debriefing in alcohol dependence treatment: illustrating key change phenomena through qualitative content analysis of clinical sessions
EM Nielson, DG May, AA Forcehimes… - Frontiers in …, 2018 - frontiersin.org
Research on the clinical applications of psychedelic-assisted psychotherapy has
demonstrated promising early results for treatment of alcohol dependence. Detailed …
demonstrated promising early results for treatment of alcohol dependence. Detailed …
Evaluation of drinking risk levels as outcomes in alcohol pharmacotherapy trials: a secondary analysis of 3 randomized clinical trials
DE Falk, SS O'Malley, K Witkiewitz, RF Anton… - JAMA …, 2019 - jamanetwork.com
Importance The US Food and Drug Administration recognizes total abstinence and no heavy
drinking days as outcomes for pivotal pharmacotherapy trials for alcohol use disorder (AUD) …
drinking days as outcomes for pivotal pharmacotherapy trials for alcohol use disorder (AUD) …
[HTML][HTML] Potential therapeutic effects of psilocybin
MW Johnson, RR Griffiths - Neurotherapeutics, 2017 - Springer
Psilocybin and other 5-hydroxytryptamine 2A agonist classic psychedelics have been used
for centuries as sacraments within indigenous cultures. In the mid-twentieth century they …
for centuries as sacraments within indigenous cultures. In the mid-twentieth century they …