[HTML][HTML] The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins

PM Brunner, M Suárez-Fariñas, H He, K Malik… - Scientific reports, 2017 - nature.com
Beyond classic “allergic”/atopic comorbidities, atopic dermatitis (AD) emerges as systemic
disease with increased cardiovascular risk. To better define serum inflammatory and …

The proteomic skin profile of moderate-to-severe atopic dermatitis patients shows an inflammatory signature

AB Pavel, L Zhou, A Diaz, B Ungar, J Dan, H He… - Journal of the American …, 2020 - Elsevier
Background Moderate-to-severe atopic dermatitis (AD) is increasingly recognized as a
systemic disease, largely due to proteomic blood studies. There are growing efforts to …

Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis

H He, R Li, S Choi, L Zhou, A Pavel, YD Estrada… - Annals of Allergy …, 2020 - Elsevier
Background Atopic dermatitis (AD) is associated with increased systemic inflammation and
cardiovascular risk. Although previous studies have found increased inflammatory proteins …

Age of onset defines two distinct profiles of atopic dermatitis in adults

P Facheris, JC Da Rosa, AD Pagan, M Angelov… - Allergy, 2023 - Wiley Online Library
Background The incidence of adult‐onset atopic dermatitis (AOAD) is increasing. However,
the unique characteristics of AOAD compared to pediatric‐onset AD persisting into …

Proteomic characterization of atopic dermatitis blood from infancy to adulthood

E Del Duca, Y Renert-Yuval, AB Pavel… - Journal of the American …, 2023 - Elsevier
Background Patients with atopic dermatitis (AD) have systemic biomarker dysregulation that
differs by age group; however, the proteomic characteristics of these age-based changes …

[HTML][HTML] Association of atopic dermatitis with cardiovascular risk factors and diseases

M Standl, F Tesch, H Baurecht, E Rodríguez… - Journal of Investigative …, 2017 - Elsevier
Epidemiological studies suggested an association between atopic dermatitis (AD) and
cardiovascular disease. Therefore, we investigate associations and potential underlying …

Mild atopic dermatitis lacks systemic inflammation and shows reduced nonlesional skin abnormalities

H He, E Del Duca, A Diaz, HJ Kim… - Journal of Allergy and …, 2021 - Elsevier
Background Molecular studies in atopic dermatitis (AD) are largely restricted to patients with
moderate-to-severe disease. Objective Our aim was to evaluate skin and blood …

[HTML][HTML] Potential biomarkers of atopic dermatitis

L Yu, L Li - Frontiers in Medicine, 2022 - frontiersin.org
Atopic dermatitis (AD) is a chronic, recurrent inflammatory skin disease with a wide range of
heterogeneity. Accurate biomarkers or predictors are the keys to instructing personalized …

Moving toward endotypes in atopic dermatitis: identification of patient clusters based on serum biomarker analysis

JL Thijs, I Strickland, CAFM Bruijnzeel-Koomen… - Journal of Allergy and …, 2017 - Elsevier
Background Atopic dermatitis (AD) is a complex, chronic, inflammatory skin disease with a
diverse clinical presentation. However, it is unclear whether this diversity exists at a …

The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease

PM Brunner, H He, AB Pavel, T Czarnowicki… - Journal of the American …, 2019 - Elsevier
Background Despite increasing evidence that adults with long-standing atopic dermatitis
(AD) have systemic inflammation, little is known about systemic inflammation in recent-onset …