Background In this study, we tested the hypothesis that a combined adipose-derived
mesenchymal stem cell (ADMSC) and ADMSC-derived exosome therapy protected rat …

Background Reactive oxygen species are important mediators exerting toxic effects on
various organs during ischemia-reperfusion (IR) injury. We hypothesized that adipose …

Background Acute kidney injury (AKI) is a critical condition for kidney and other remote
organs, including the lung. However, available treatments for AKI are limited. In this study …

Background. Acute kidney injury (AKI) represents a major clinical problem with high mortality
and limited causal treatments. The use of cell therapy has been suggested as a potential …

Background/Aims: The therapeutic potential of extracellular vesicles (EVs) derived from
mesenchymal stromal cells (MSCs) in kidney injury has been largely reported. However …

Stem cell-based therapy has been suggested as a promising option for the treatment of
renal ischemia-reperfusion injury (IRI). However, how to efficiently deliver stem cells remains …

Aims To investigate the protective function of exosomes from adipose tissue-derived
mesenchymal stem cells (AMSCs) in sepsis-induced acute kidney injury (AKI) in mice and …

Mesenchymal stem cells (MSCs) and their secreted exosomes exert a cardioprotective role
in jeopardized myocardium. However, the specific effects and underlying mechanisms of …

Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …

Background/Aims: Acute kidney injury (AKI) is a common clinical condition that can lead to
chronic kidney failure. Although mesenchymal stem cell-derived extracellular vesicles (MSC …