Intraocular pressure (IOP) is regulated primarily through aqueous humor production by
ciliary body and drainage through uveoscleral and trabecular meshwork (TM) tissues. The …

The purpose of this study was to investigate the effects of abnormal-cannabidiol (abn-cbd), a
non-psychoactive cannabinoid agonist, on aqueous humor outflow via the trabecular …

Background and purpose: Trabecular meshwork (TM) is an ocular tissue involved in the
regulation of aqueous humour outflow and intraocular pressure (IOP). CB1 receptors (CB1) …

purpose. To study the effects of 2-arachidonyl glyceryl ether (noladin ether), an
endocannabinoid ligand selective for cannabinoid (CB) 1 receptor, on aqueous humor …

purpose. To study the effects of JWH015, a CB2-selective agonist, on aqueous humor
outflow facility, to investigate whether functional CB2 cannabinoid receptors are expressed …

Objectives Glaucoma is characterized by progressive damage of the retinal ganglion cells
(RGCs), resulting in irreversible vision loss. Cannabinoids (CBs) ameliorate several factors …

Glaucoma is a blinding disease that is estimated to afflict more than 3 million Americans and
60 million globally [1, 2]. Glaucoma is a neurological disease, with the blindness developing …

Purpose: It has been known for nearly 50 years that cannabis and the psychoactive
constituent Δ 9-tetrahydrocannabinol (THC) reduce intraocular pressure (IOP). Elevated IOP …

Purpose: To study the role of CB2 cannabinoid receptors in cellular functions of trabecular
meshwork (TM) cells including cytoskeleton changes and migration and to investigate the …

This chapter focuses on the effects of cannabinoids on intraocular pressure (IOP), a major
risk factor in the development of glaucoma. A review of original papers, published in English …