CHAPTER 1 Page 1 Afr. J. Biomed. Res. Vol. 25 (May, 2022); 163 - 167 Research Article
Genetic Diversity of Plasmodium falciparum Based on Merozoite Surface Proteins 1 and 2 …

Background Plasmodium falciparum merozoite surface protein-1 (PfMSP-1) and-2 (PfMSP-
2) are major blood-stage vaccine candidate antigens. Understanding the genetic diversity of …

Introduction: The genetic make-up of malaria parasite is potent for understanding the
parasite virulence, designing antimalarial vaccine and evaluating the impact of malaria …

Understanding the genetic diversity in Plasmodium falciparum populations is of major
importance in the outcome of antimalarial drug trials and vaccine design. Merozoite surface …

A number of stage-specific antigens have been characterized for vaccine development in
Plasmodium falciparum malaria. The polymorphic merozoite surface protein 1 (MSP-1) of …

Background: Understanding the genetic diversity of Plasmodium species through
polymorphic studies can assist in designing more effective control strategies of malaria like …

A major characteristic of human malaria parasites is their genetic diversity and an increasing
number of studies have been reported on the epidemiology of Plasmodium falciparum …

The genetic diversity of typical clinical isolated Plasmodium falciparum in the malaria
population varies greatly, especially at the location where malaria disease were recorded at …

Background The genetic diversity of Plasmodium falciparum has been extensively studied in
various parts of the world. However, limited data are available from Mauritania. The present …

Mutations in merozoite surface protein 1 (MSP1) serve as indicators of genetic diversity in
Plasmodium falciparum population in a given area. Diversity in MSP1 gene of P. falciparum …