Anticancer activity of the plant flavonoid luteolin against preclinical models of various cancers and insights on different signalling mechanisms modulated

SA Ganai, FA Sheikh, ZA Baba, MA Mir… - Phytotherapy …, 2021 - Wiley Online Library
Various signaling mechanisms contribute significantly to the development of multiple
cancers. Small molecules with the potential of influencing a wide variety of molecular targets …

[HTML][HTML] Luteolin, a potent anticancer compound: from chemistry to cellular interactions and synergetic perspectives

H Singh Tuli, P Rath, A Chauhan, K Sak, D Aggarwal… - Cancers, 2022 - mdpi.com
Simple Summary Common flavonoid luteolin 3′, 4′, 5, 7-tetrahydroxyflavone has
immense potential to be utilized as a chemopreventive dietary molecule. According to …

[HTML][HTML] Therapeutic potential of luteolin on cancer

M Çetinkaya, Y Baran - Vaccines, 2023 - mdpi.com
Cancer is a global concern, as the rate of incidence is increasing each year. The challenges
related to the current chemotherapy drugs, such as the concerns related to toxicity, turn to …

[HTML][HTML] Luteolin, a flavonoid, as an anticancer agent: A review

M Imran, A Rauf, T Abu-Izneid, M Nadeem… - Biomedicine & …, 2019 - Elsevier
Many food-derived phytochemicals and their derivatives represent a cornucopia of new anti-
cancer compounds. Luteolin (3, 4, 5, 7-tetrahydroxy flavone) is a flavonoid found in different …

Molecular targets of luteolin in cancer

MJ Tuorkey - European Journal of Cancer Prevention, 2016 - journals.lww.com
Many food-derived phytochemical compounds and their derivatives represent a cornucopia
of new anticancer compounds. Despite extensive study of luteolin, the literature has no …

Luteolin, a flavonoid with potential for cancer prevention and therapy

Y Lin, R Shi, X Wang, HM Shen - Current cancer drug targets, 2008 - ingentaconnect.com
Luteolin, 3', 4', 5, 7-tetrahydroxyflavone, is a common flavonoid that exists in many types of
plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been …

Distribution and biological activities of the flavonoid luteolin

M López-Lázaro - Mini reviews in medicinal chemistry, 2009 - ingentaconnect.com
Epidemiological evidence suggests that flavonoids may play an important role in the
decreased risk of chronic diseases associated with a diet rich in plant-derived foods …

Skin cancer, including related pathways and therapy and the role of luteolin derivatives as potential therapeutics

AM Juszczak, U Wöelfle, MZ Končić… - Medicinal research …, 2022 - Wiley Online Library
Cutaneous malignant melanoma is the fastest growing and the most aggressive form of skin
cancer that is diagnosed. However, its incidence is relatively scarce compared to the highest …

Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells

S Attoub, AH Hassan, B Vanhoecke, R Iratni… - European journal of …, 2011 - Elsevier
Phytochemical compounds and histone deacetylase (HDAC) inhibitors are emerging as a
new generation of anticancer agents with limited toxicity in cancer patients. We investigated …

Luteolin induces cell cycle arrest and apoptosis through extrinsic and intrinsic signaling pathways in MCF-7 breast cancer cells

SH Park, S Ham, TH Kwon, MS Kim… - Journal of …, 2014 - dl.begellhouse.com
Luteolin is a common flavonoid that exists in medicinal herbs, fruits, and vegetables.
Luteolin has biochemical functions including anti-allergy, anti-inflammation, and anti-cancer …