Epidemiology of Barrett's esophagus and esophageal adenocarcinoma

TM Runge, JA Abrams… - Gastroenterology Clinics, 2015 - gastro.theclinics.com
Barrett's esophagus (BE) is a condition in which the typical squamous epithelium of the
esophageal mucosa is replaced with columnar intestinal epithelium. 1, 2 BE is a known …

Barrett's esophagus and esophageal adenocarcinoma: how common are they really?

AP Thrift - Digestive diseases and sciences, 2018 - Springer
Since the early 1970s, the incidence of esophageal adenocarcinoma (EA) has increased
dramatically in most Western populations while the incidence of esophageal squamous cell …

Global burden and epidemiology of Barrett oesophagus and oesophageal cancer

AP Thrift - Nature reviews Gastroenterology & hepatology, 2021 - nature.com
Oesophageal cancer is a global health problem; in 2018 there were more than 572,000
people newly diagnosed with oesophageal cancer worldwide. There are two main …

Focus on Barrett's esophagus and esophageal adenocarcinoma

TG Paulson, BJ Reid - Cancer cell, 2004 - cell.com
Esophageal malignancies are the sixth leading cause of cancer death in the world.
Esophageal cancers represent about 1 percent of the cancers diagnosed in the US, with an …

Risk factors for the development of esophageal adenocarcinoma in Barrett's esophagus

PJF De Jonge, EW Steyerberg, EJ Kuipers… - Official journal of the …, 2006 - journals.lww.com
METHODS A hospital-based case-control study was performed in which 91 cases with EAC
and 244 controls with histologically confirmed BE (> 2 cm) with no dysplasia or low-grade …

Barrett's esophagus and esophageal adenocarcinoma: pathogenesis, diagnosis, and therapy

SJ Spechler - Medical Clinics, 2002 - medical.theclinics.com
Gastric juice that refluxes into the esophagus can injure esophageal squamous epithelium.
When the injury heals through a metaplastic process in which an abnormal columnar …

Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis

BJ Reid, X Li, PC Galipeau, TL Vaughan - Nature reviews Cancer, 2010 - nature.com
The public health importance of Barrett's oesophagus lies in its association with
oesophageal adenocarcinoma. The incidence of oesophageal adenocarcinoma has risen at …

Barrett esophagus and risk of esophageal cancer: a clinical review

SJ Spechler - Jama, 2013 - jamanetwork.com
Importance Barrett esophagus, a complication of gastroesophageal reflux disease (GERD),
predisposes patients to esophageal adenocarcinoma, a tumor that has increased in …

Predictors of progression in Barrett's esophagus: current knowledge and future directions

GA Prasad, A Bansal, P Sharma… - Official journal of the …, 2010 - journals.lww.com
Barrett's esophagus (BE) is the strongest risk factor for esophageal adenocarcinoma (EAC),
a malignancy with persistently poor long-term outcomes. EAC is thought to develop through …

Barrett's oesophagus: epidemiology, cancer risk and implications for management

PJF De Jonge, M van Blankenstein, WM Grady… - Gut, 2014 - gut.bmj.com
Although endoscopic surveillance of patients with Barrett's oesophagus has been widely
implemented, its effectiveness is debateable. The recently reported low annual oesophageal …