BackgroundThe efficacy of psychopharmacological treatments has been called into
question. Psychiatrists are unfamiliar with the effectiveness of common medical drugs …

Importance There is debate about the effectiveness of psychiatric treatments and whether
pharmacotherapy or psychotherapy should be primarily used. Objectives To perform a …

OBJECTIVE: The author sought to illustrate the invalidity of meta-analyses that claim to
quantitatively compare the benefits of psychotherapy to pharmacotherapy in patients with …

Mental disorders represent a worldwide public health concern. Psychotherapies and
pharmacotherapies are recommended as first line treatments. However, evidence has …

Randomised controlled trials (RCTs) are considered the 'gold standard'by which novel
psychotropic medications and psychological interventions are evaluated and consequently …

Despite considerable progress in pharmacotherapy over the past seven decades, many
mental disorders remain insufficiently treated. This situation is in part due to the limited …

In recent years there has been much debate regarding the evaluation of treatments in
medicine. The evidence-based medicine (EBM) movement has formed partly out of the …

It is not yet clear what mental disorders are and what are the causal pathways that lead to
them. That makes it difficult to decide what the targets and outcomes of psychotherapies …

At last–a new edition of the highly acclaimed book Clinical Trials in Psychiatry This book
provides a concise but thorough overview of clinical trials in psychiatry, invaluable to those …

BACKGROUND AND OBJECTIVE: Meta-analyses of randomized trials may incorporate new
evidence, and estimated treatment effects change over time. We evaluated whether the …