Identification of individuals by trait prediction using whole-genome sequencing data
C Lippert, R Sabatini, MC Maher… - Proceedings of the …, 2017 - National Acad Sciences
Prediction of human physical traits and demographic information from genomic data
challenges privacy and data deidentification in personalized medicine. To explore the …
challenges privacy and data deidentification in personalized medicine. To explore the …
Genome privacy: challenges, technical approaches to mitigate risk, and ethical considerations in the United States
Accessing and integrating human genomic data with phenotypes are important for
biomedical research. Making genomic data accessible for research purposes, however …
biomedical research. Making genomic data accessible for research purposes, however …
[HTML][HTML] Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits
I Tachmazidou, D Süveges, JL Min, GRS Ritchie… - The American Journal of …, 2017 - cell.com
Deep sequence-based imputation can enhance the discovery power of genome-wide
association studies by assessing previously unexplored variation across the common-and …
association studies by assessing previously unexplored variation across the common-and …
[HTML][HTML] On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy
Recent advances in genome-scale, system-level measurements of quantitative phenotypes
(transcriptome, metabolome, and proteome) promise to yield unprecedented biological …
(transcriptome, metabolome, and proteome) promise to yield unprecedented biological …
[HTML][HTML] The 1000 Genomes Project: new opportunities for research and social challenges
Abstract The 1000 Genomes Project, an international collaboration, is sequencing the whole
genome of approximately 2,000 individuals from different worldwide populations. The …
genome of approximately 2,000 individuals from different worldwide populations. The …
Privacy in the genomic era
Genome sequencing technology has advanced at a rapid pace and it is now possible to
generate highly-detailed genotypes inexpensively. The collection and analysis of such data …
generate highly-detailed genotypes inexpensively. The collection and analysis of such data …
An overview of human genetic privacy
The study of human genomics is becoming a Big Data science, owing to recent
biotechnological advances leading to availability of millions of personal genome sequences …
biotechnological advances leading to availability of millions of personal genome sequences …
[HTML][HTML] Limitations of the human reference genome for personalized genomics
Data from the 1000 genomes project (1KGP) and Complete Genomics (CG) have
dramatically increased the numbers of known genetic variants and challenge several …
dramatically increased the numbers of known genetic variants and challenge several …
[HTML][HTML] Public access to genome-wide data: five views on balancing research with privacy and protection
Just over twelve months ago, PLoS Genetics published a paper [1] demonstrating that, given
genome-wide genotype data from an individual, it is, in principle, possible to ascertain …
genome-wide genotype data from an individual, it is, in principle, possible to ascertain …