Hepatic ischemia–reperfusion injury (HIRI) is a major complication of liver resection or liver
transplantation that can seriously affect patient's prognosis. There is currently no definitive …

Transient ischaemia and reperfusion in liver tissue induce hepatic ischaemia/reperfusion
(I/R) tissue injury and a profound inflammatory response in vivo. Hepatic I/R can be …

Liver ischemia‐reperfusion (I‐R) injury occurs during liver resection, liver transplantation,
and hemorrhagic shock. The main mode of liver cell death after warm and/or cold liver I‐R is …

Ischemia-reperfusion injury (IRI) is a common clinical consequence of hepatic surgery,
cardiogenic shock, and liver transplantation. A steatotic liver is particularly vulnerable to IRI …

Autophagy plays an important role in cell survival, sequestering, and degrading a wide
variety of substrates. Although an increase of autophagosomes in liver has been reported in …

Background Hepatic ischemia/reperfusion is a multi-factorial process which causes liver
injury. It is reported that ischemia alone is sufficient to induce liver injury. Nutrient deprivation …

Apoptosis is a primary characteristic in the pathogenesis of liver disease. Hepatic apoptosis
is regulated by autophagic activity. However, mechanisms mediating their interaction remain …

In performing our experiment, impaired autophagy increased hepatocellular damage during
the reperfusion period. It was demonstrated by the effect of blocking autophagy using …

As a highly evolutionarily conserved process, autophagy can be found in all types of
eukaryotic cells. Such a constitutive process maintains cellular homeostasis in a wide variety …

Ischemia/reperfusion (I/R) injury remains a major complication of liver resection,
transplantation, and hemorrhagic shock. Although the mechanisms that contribute to hepatic …