SOX4 is a pivotal regulator of tumorigenesis in differentiated thyroid cancer

CY Kuo, YC Hsu, CL Liu, YS Li, SC Chang… - Molecular and Cellular …, 2023 - Elsevier
The SOX family consists of about 20 transcription factors involved in embryonic
development, reprogramming, and cell fate determination. In this study, we demonstrated …

[HTML][HTML] Knockdown of SOX9 inhibits the proliferation, invasion, and EMT in thyroid cancer cells

J Huang, L Guo - Oncology research, 2017 - ncbi.nlm.nih.gov
Sex-determining region Y (SRY)-box 9 (SOX9) is a member of the SOX transcription factor
family. Increasing evidence has reported that SOX9 plays different roles in various types of …

Expression of Sox2 in human cervical carcinogenesis

J Ji, PS Zheng - Human pathology, 2010 - Elsevier
Sox2 is a key transcription factor for embryonic development and plays a critical role in
determining the fate of stem cells. Recently, Sox2 has been detected in several human …

[HTML][HTML] SOX15 and other SOX family members are important mediators of tumorigenesis in multiple cancer types

KL Thu, DD Becker-Santos, N Radulovich, LA Pikor… - …, 2014 - ncbi.nlm.nih.gov
SOX genes are transcription factors with important roles in embryonic development and
carcinogenesis. The SOX family of 20 genes is responsible for regulating lineage and tissue …

Sox10 expression in ovarian epithelial tumors is associated with poor overall survival

AY Kwon, I Heo, HJ Lee, G Kim, H Kang, JH Heo… - Virchows Archiv, 2016 - Springer
Sox10 is a transcription factor regulating the development of several cell lineages and is
involved in tumor development. However, the clinicopathological relevance of Sox10 …

Sox9 is involved in the thyroid differentiation program and is regulated by crosstalk between TSH, TGFβ and thyroid transcription factors

A López-Márquez, C Carrasco-López… - Scientific reports, 2022 - nature.com
While the signaling pathways and transcription factors involved in the differentiation of
thyroid follicular cells, both in embryonic and adult life, are increasingly well understood, the …

[HTML][HTML] SOX12 promotes thyroid cancer cell proliferation and invasion by regulating the expression of POU2F1 and POU3F1

Z Su, W Bao, G Yang, J Liu, B Zhao - Yonsei Medical Journal, 2022 - ncbi.nlm.nih.gov
Purpose SOX12 is overexpressed in many cancers, and we aimed to explore the biological
function and mechanism of SOX12 in thyroid cancer. Materials and Methods We first …

SOX18 exerts tumor-suppressive functions in papillary thyroid carcinoma through inhibition of Wnt/β-catenin signaling

Q Geng, H Deng, J Fu, F Cui - Experimental Cell Research, 2020 - Elsevier
Sex-determining region on the Y chromosome-related high mobility group box 18 (SOX18)
has emerged as a key tumor-related protein in a wide range of human tumors. Yet, the …

Clinical significance and prognostic value of SOX7 expression in liver and pancreatic carcinoma

J Wang, S Zhang, J Wu, Z Lu… - Molecular …, 2017 - spandidos-publications.com
Sex determining region Y‑box 7 (SOX7) is known to function as a tumor suppressor in a
number of types of cancer; however, its role in liver and pancreatic carcinoma remains …

SOX 2 Expression in Human Pituitary Adenomas–Correlations With Pituitary Function

C Capatina, AM Cimpean, M Raica, M Coculescu… - in vivo, 2019 - iv.iiarjournals.org
Background/Aim: The aim of this study was to evaluate SOX2 expression in pituitary
adenomas and its correlation to their secretory state and clinicopathological parameters …