The most common medical cause of major blood loss is surgery, particularly cardiovascular
procedures, liver transplantation and hepatic resection, and major orthopedic procedures …

Excess perioperative bleeding remains a major complication following surgery, resulting in
increased morbidity and mortality. The principal causes of non-surgical haemostatic …

Purpose. The pharmacology, clinical efficacy, adverse effects and toxicities, drug
interactions, dosage and administration, and safety issues related to the use of absorbable …

Skilful surgery combined with blood-saving methods and careful management of blood
coagulation will all help reduce unnecessary blood loss and transfusion requirements …

The definition of major bleeding varies between studies on surgical patients, particularly
regarding the criteria for surgical wound‐related bleeding. This diversity contributes to the …

The goal of this review is to briefly summarize the two primary pathways of hemostasis,
primary hemostasis and secondary hemostasis, as well as to summarize anticoagulant …

Objective: To address the clinical and regulatory challenges of optimal primary endpoints for
bleeding patients by developing consensus-based recommendations for primary clinical …

Bleeding is an important issue in cardiothoracic surgery, and about 20% of all blood
products are transfused in this clinical setting worldwide. Transfusion practices, however …

A variety of definitions of major bleeding have been used in published clinical studies, and
this diversity adds to the difficulty in comparing data between trials and in performing meta …

Perioperative bleeding remains a major complication during and after surgery, resulting in
increased morbidity and mortality. The principal causes of non-vascular sources of …