KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
A Kumar, Y Lyu, Y Yanagihashi, C Chantarasrivong… - Cell reports, 2022 - cell.com
Kaposi sarcoma-associated herpesvirus (KSHV) establishes a latent infection in the cell
nucleus, but where KSHV episomal genomes are tethered and the mechanisms underlying …
nucleus, but where KSHV episomal genomes are tethered and the mechanisms underlying …
Epigenetic regulation of Kaposi's sarcoma-associated herpesvirus latency
M Campbell, WS Yang, WW Yeh, CH Kao… - Frontiers in …, 2020 - frontiersin.org
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic γ-herpesvirus that infects
humans and exhibits a biphasic life cycle consisting of latent and lytic phases. Following …
humans and exhibits a biphasic life cycle consisting of latent and lytic phases. Following …
Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage
Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is a human gammaherpesvirus
recognized as the principal causative agent of KS and primary effusion lymphoma (PEL) …
recognized as the principal causative agent of KS and primary effusion lymphoma (PEL) …
Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomes
A Krithivas, M Fujimuro, M Weidner, DB Young… - Journal of …, 2002 - Am Soc Microbiol
Maintenance of Kaposi's sarcoma-associated herpesvirus (KSHV) latent infection depends
on the viral episomes in the nucleus being distributed to daughter cells following cell …
on the viral episomes in the nucleus being distributed to daughter cells following cell …
Biphasic Euchromatin-to-Heterochromatin Transition on the KSHV Genome Following De Novo Infection
The establishment of latency is an essential step for the life-long persistent infection and
pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV). While the KSHV …
pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV). While the KSHV …
Kaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistence
Q Sun, T Tsurimoto, F Juillard, L Li… - Proceedings of the …, 2014 - National Acad Sciences
Kaposi's sarcoma-associated herpesvirus (KSHV) latently infects tumor cells and persists as
a multiple-copy, extrachromosomal, circular episome. To persist, the viral genome must …
a multiple-copy, extrachromosomal, circular episome. To persist, the viral genome must …
Site-specific association with host and viral chromatin by Kaposi's sarcoma-associated herpesvirus LANA and its reversal during lytic reactivation
A Mercier, C Arias, AS Madrid, MM Holdorf… - Journal of …, 2014 - Am Soc Microbiol
Latency-associated nuclear antigen (LANA), a multifunctional protein expressed by the
Kaposi sarcoma-associated herpesvirus (KSHV) in latently infected cells, is required for …
Kaposi sarcoma-associated herpesvirus (KSHV) in latently infected cells, is required for …
KSHV genome replication and maintenance
P Purushothaman, P Dabral, N Gupta… - Frontiers in …, 2016 - frontiersin.org
Kaposi's sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a
major etiological agent for multiple severe malignancies in immune-compromised patients …
major etiological agent for multiple severe malignancies in immune-compromised patients …
Bub1 and CENP-F can contribute to Kaposi's sarcoma-associated herpesvirus genome persistence by targeting LANA to kinetochores
The latency-associated nuclear antigen (LANA) encoded by Kaposi's sarcoma-associated
herpesvirus (KSHV) is critical for segregation of viral episomes to progeny nuclei and allows …
herpesvirus (KSHV) is critical for segregation of viral episomes to progeny nuclei and allows …
The 3D structure of Kaposi sarcoma herpesvirus LANA C-terminal domain bound to DNA
J Hellert, M Weidner-Glunde… - Proceedings of the …, 2015 - National Acad Sciences
Kaposi sarcoma herpesvirus (KSHV) persists as a latent nuclear episome in dividing host
cells. This episome is tethered to host chromatin to ensure proper segregation during …
cells. This episome is tethered to host chromatin to ensure proper segregation during …