RGD-decorated PLGA nanoparticles improved effectiveness and safety of cisplatin for lung cancer therapy
Upon extensive pharmaceutical and biomedical research to treat lung cancer indicates that
lung cancer remains one of the deadliest diseases and the leading cause of death in men …
lung cancer remains one of the deadliest diseases and the leading cause of death in men …
Repurposing itraconazole loaded PLGA nanoparticles for improved antitumor efficacy in non-small cell lung cancers
NA Alhakamy, S Md - Pharmaceutics, 2019 - mdpi.com
Itraconazole (ITR) is a broad-spectrum antifungal drug, which has been shown to possess
some promising anticancer, anti-proliferative, and anti-angiogenic properties in some …
some promising anticancer, anti-proliferative, and anti-angiogenic properties in some …
[HTML][HTML] Gefitinib loaded PLGA and chitosan coated PLGA nanoparticles with magnified cytotoxicity against A549 lung cancer cell lines
AS Alshetaili - Saudi journal of biological sciences, 2021 - Elsevier
In the current study, gefitinib loaded PLGA nanoparticles (GFT-PLGA-NPs) and chitosan
coated PLGA nanoparticles (GFT-CS-PLGA-NPs) were synthesized to investigate the role of …
coated PLGA nanoparticles (GFT-CS-PLGA-NPs) were synthesized to investigate the role of …
Novel silibinin loaded chitosan-coated PLGA/PCL nanoparticles based inhalation formulations with improved cytotoxicity and bioavailability for lung cancer
Silibinin is widely used as an anticancer agent. There are important matters of concern
regarding the drug pharmacokinetics related to the conventional formulation due to their low …
regarding the drug pharmacokinetics related to the conventional formulation due to their low …
A novel combination for the treatment of small cell lung cancer: Active targeted irinotecan and stattic co-loaded PLGA nanoparticles
FB Arslan, K Öztürk, E Tavukçuoğlu, SC Öztürk… - International Journal of …, 2023 - Elsevier
Polymeric nanoparticles are widely used drug delivery systems for cancer treatment due to
their properties such as ease of passing through biological membranes, opportunity to …
their properties such as ease of passing through biological membranes, opportunity to …
Oral delivery of DMAB-modified docetaxel-loaded PLGA-TPGS nanoparticles for cancer chemotherapy
Three types of nanoparticle formulation from biodegradable PLGA-TPGS random copolymer
were developed in this research for oral administration of anticancer drugs, which include …
were developed in this research for oral administration of anticancer drugs, which include …
Targeted delivery of monoclonal antibody conjugated docetaxel loaded PLGA nanoparticles into EGFR overexpressed lung tumour cells
J Patel, J Amrutiya, P Bhatt, A Javia… - Journal of …, 2018 - Taylor & Francis
The aim of this study was to develop anti-EGFR antibody conjugated poly (lactide-co-
glycolide) nanoparticles (NPs) to target epidermal growth factor receptor, highly expressed …
glycolide) nanoparticles (NPs) to target epidermal growth factor receptor, highly expressed …
Formulation, optimization, hemocompatibility and pharmacokinetic evaluation of PLGA nanoparticles containing paclitaxel
Abstract Objective: Paclitaxel (PTX)-loaded polymer (Poly (lactic-co-glycolic acid), PLGA)-
based nanoformulation was developed with the objective of formulating cremophor EL-free …
based nanoformulation was developed with the objective of formulating cremophor EL-free …
Co-administration of iRGD enhances tumor-targeted delivery and anti-tumor effects of paclitaxel-loaded PLGA nanoparticles for colorectal cancer treatment
Y Zhong, T Su, Q Shi, Y Feng, Z Tao… - International journal …, 2019 - Taylor & Francis
Background Nanoparticles exhibit great promise for improving the solubility and tissue-
specific distribution of chemotherapeutic agents; however, the passive and highly variable …
specific distribution of chemotherapeutic agents; however, the passive and highly variable …
Chemodrug delivery using integrin-targeted PLGA-Chitosan nanoparticle for lung cancer therapy
In this study, we report the efficacy of RGD (arginine-glycine-aspartic acid) peptide-modified
polylactic acid-co-glycolic acid (PLGA)-Chitosan nanoparticle (CSNP) for integrin αvβ3 …
polylactic acid-co-glycolic acid (PLGA)-Chitosan nanoparticle (CSNP) for integrin αvβ3 …