The stability and change of etiological influences on depression, anxiety symptoms and their co-occurrence across adolescence and young adulthood

MA Waszczuk, HMS Zavos, AM Gregory… - Psychological …, 2016 - cambridge.org
Background. Depression and anxiety persist within and across diagnostic boundaries. The
manner in which common v. disorder-specific genetic and environmental influences operate …

Polygenic risk for depression, anxiety and neuroticism are associated with the severity and rate of change in depressive symptoms across adolescence

ASF Kwong, TT Morris, RM Pearson… - Journal of Child …, 2021 - Wiley Online Library
Background Adolescence marks a period where depression will commonly onset. Twin
studies show that genetic influences play a role in how depression develops and changes …

Symptoms of anxiety and depression in young adults: genetic and environmental influences on stability and change

RB Nes, E Røysamb… - Twin Research and …, 2007 - cambridge.org
Etiological factors for stability and change in symptoms of anxiety and depression, including
sex differences, are largely unexplored in young adults. Using biometric modeling and two …

Genetic and environmental risk factors associated with trajectories of depression symptoms from adolescence to young adulthood

ASF Kwong, JA López-López, G Hammerton… - JAMA Network …, 2019 - jamanetwork.com
Importance Less favorable trajectories of depressive mood from adolescence to early
adulthood are associated with current and later psychopathology, impaired educational …

Estimating genetic and environmental influences on depressive symptoms in adolescence: Differing effects on higher and lower levels of symptoms

R Rende, C Slomkowski… - Journal of Clinical …, 2006 - Taylor & Francis
We estimate the relative effect sizes of genetic and environmental influences on both higher
and lower levels of depressive symptoms with attention to persistence over a 1-year period …

The phenotypic and genetic structure of depression and anxiety disorder symptoms in childhood, adolescence, and young adulthood

MA Waszczuk, HMS Zavos, AM Gregory… - JAMA psychiatry, 2014 - jamanetwork.com
Importance TheDSM-5classifies mood and anxiety disorders as separate conditions.
However, some studies in adults find a unidimensional internalizing factor that underpins …

Unraveling the genetic and environmental relationship between well-being and depressive symptoms throughout the lifespan

BML Baselmans, YE Willems… - Frontiers in …, 2018 - frontiersin.org
Whether well-being and depressive symptoms can be considered as two sides of the same
coin is widely debated. The aim of this study was to gain insight into the etiology of the …

Genetic susceptibility for major depressive disorder associates with trajectories of depressive symptoms across childhood and adolescence

AA Lussier, M Hawrilenko, MJ Wang… - Journal of Child …, 2021 - Wiley Online Library
Background Early‐onset depression during childhood and adolescence is associated with a
worse course of illness and outcome than adult onset. However, the genetic factors that …

Gene–environment interplay in depressive symptoms: Moderation by age, sex, and physical illness

AJ Petkus, CR Beam, W Johnson, J Kaprio… - Psychological …, 2017 - cambridge.org
BackgroundNumerous factors influence late-life depressive symptoms in adults, many not
thoroughly characterized. We addressed whether genetic and environmental influences on …

Genetics of childhood and adolescent depression: insights into etiological heterogeneity and challenges for future genomic research

F Rice - Genome Medicine, 2010 - Springer
There is heterogeneity between depression in childhood, adolescence and adulthood in
terms of the gender composition of affected cases, prevalence, rates of recurrence and risk …