pyCEPS: A cross-platform Electroanatomic Mapping Data to Computational Model Conversion Platform for the Calibration of Digital Twin Models of Cardiac …

R Arnold, AJ Prassl, A Neic, F Thaler… - arXiv preprint arXiv …, 2024 - arxiv.org
Background and Objective: Data from electro-anatomical mapping (EAM) systems are
playing an increasingly important role in computational modeling studies for the patient …

Towards the development of virtual heart technology for creating digital twins of cardiac electrophysiology

MAF Gsell, L Azzolin, KK Gillette, A Neic… - 2023 Computing in …, 2023 - ieeexplore.ieee.org
Introduction: Virtual heart technologies (VHTs) promise to offer an detailed view on cardiac
electrophysiology (EP). However, only very few VHTs simulating EP of four-chamber hearts …

Quantifying variabilities in cardiac digital twin models of the electrocardiogram

E Zappon, MAF Gsell, K Gillette, G Plank - arXiv preprint arXiv:2407.17146, 2024 - arxiv.org
CDT of human cardiac EP are digital replicas of patient hearts that match like-for-like clinical
observations. The ECG, as the most prevalent non-invasive observation of cardiac …

Personalized Topology-Informed 12-Lead ECG Electrode Localization from Incomplete Cardiac MRIs for Efficient Cardiac Digital Twins

L Li, H Smith, Y Lyu, J Camps, B Rodriguez… - arXiv preprint arXiv …, 2024 - arxiv.org
Cardiac digital twins (CDTs) offer personalized\textit {in-silico} cardiac representations for
the inference of multi-scale properties tied to cardiac mechanisms. The creation of CDTs …

Digital twinning of cardiac electrophysiology models from the surface ECG: a geodesic backpropagation approach

T Grandits, J Verhülsdonk, G Haase… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
The eikonal equation has become an indispensable tool for modeling cardiac electrical
activation accurately and efficiently. In principle, by matching clinically recorded and eikonal …

[HTML][HTML] A framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs

K Gillette, MAF Gsell, AJ Prassl, E Karabelas… - Medical image …, 2021 - Elsevier
Abstract Cardiac digital twins (Cardiac Digital Twin (CDT) s) of human electrophysiology
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …

Deep computational model for the inference of ventricular activation properties

L Li, J Camps, A Banerjee, M Beetz… - … Workshop on Statistical …, 2022 - Springer
Patient-specific cardiac computational models are essential for the efficient realization of
precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can …

EP-Net: learning cardiac electrophysiology models for physiology-based constraints in data-driven predictions

I Ayed, N Cedilnik, P Gallinari, M Sermesant - Functional Imaging and …, 2019 - Springer
Cardiac electrophysiology (EP) models achieved good pro gress in simulating cardiac
electrical activity. However numerical issues and computational times hamper clinical …

Digital twinning of cardiac electrophysiology for congenital heart disease

M Salvador, F Kong, M Peirlinck… - Journal of the …, 2024 - royalsocietypublishing.org
In recent years, blending mechanistic knowledge with machine learning has had a major
impact in digital healthcare. In this work, we introduce a computational pipeline to build …

Deep learning-based emulation of human cardiac activation sequences

A Bertrand, J Camps, V Grau, B Rodriguez - International Conference on …, 2023 - Springer
The vision of digital twins for precision cardiology is to combine expert knowledge and data
of patients' cardiac pathophysiology with advanced computational methods, in order to …