[HTML][HTML] Generalisability and potential deaths averted from intensive blood pressure treatment among the elderly population in the US and China: A nationally …

C Li, C Yang, F Shao, X Liang, K Chen… - Journal of Global …, 2023 - ncbi.nlm.nih.gov
Background The Systolic Blood Pressure Intervention Trial (SPRINT) from the US and the
Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) trial from …

Control of blood pressure and risk of cardiovascular disease and mortality in elderly Chinese: a real-world prospective cohort study

A Wang, X Tian, Y Zuo, S Chen, Y Zhang, X Zhang… - …, 2022 - Am Heart Assoc
Background: The STEP trial (Strategy of Blood Pressure Intervention in the Elderly
Hypertensive Patients) showed that older hypertensive patients might benefit from a target …

[HTML][HTML] Intensive blood pressure control for patients aged over 60: A meta-analysis of the SPRINT, STEP, and ACCORD BP randomized controlled trials

X Li, J Zhang, Z Xing, Q Liu, S Zhou, Y Xiao - Maturitas, 2023 - Elsevier
Objectives To evaluate the effects of intensive treatment to lower blood pressure (BP) on the
risk of cardiovascular disease (CVD) among patients aged over 60 years. Study design We …

[HTML][HTML] Strategy of blood pressure intervention in the elderly hypertensive patients (STEP): Rational, design, and baseline characteristics for the main trial

S Zhang, S Wu, J Ren, X Chen, X Zhang, Y Feng… - Contemporary Clinical …, 2020 - Elsevier
The optimal systolic blood pressure (SBP) treatment target in elderly people is full of
challenge, and non-adherence is one major cause of uncontrolled BP. The Strategy of Blood …

Assessment of long-term benefit of intensive blood pressure control on residual life span: secondary analysis of the Systolic Blood Pressure Intervention Trial (SPRINT …

M Vaduganathan, BL Claggett, SP Juraschek… - JAMA …, 2020 - jamanetwork.com
Importance High blood pressure (BP) is a leading contributor to premature mortality
worldwide. The Systolic Blood Pressure Intervention Trial (SPRINT) demonstrated a 27 …

Cost-effectiveness of intensive versus standard blood pressure treatment in older patients with hypertension in China

J Fan, W Zheng, W Liu, J Xu, L Zhou, S Liu, J Bai… - …, 2022 - Am Heart Assoc
Background: In the STEP trial (Strategy of Blood Pressure Intervention in older Hypertensive
Patients), the risk of cardiovascular events is significantly lower in patients who received …

Intensive Blood Pressure Control and Cardiovascular Outcomes in Elderly Patients: A Secondary Analysis of SPRINT Study Based on a 60-Year Age Cutoff

MF Cheema, Z Butt, S Gilani, S Shafiq… - American Journal of …, 2023 - academic.oup.com
Background In the original SPRINT article, age was categorized at 75 years, which was
contrary to many previous clinical trials which is at 60 years. Methods The SPRINT trial …

[HTML][HTML] STEP to blood pressure management of elderly hypertension: evidence from Asia

W Zhang, J Cai - Hypertension Research, 2022 - nature.com
With a rapidly aging population, adequate blood pressure (BP) control is critical for
hypertension management and prevention of cardiovascular events. Impressive …

Intensive blood pressure lowering in different age categories: insights from the Systolic Blood Pressure Intervention Trial

C Byrne, M Pareek, M Vaduganathan… - European Heart …, 2020 - academic.oup.com
Abstract Aims The 2018 ESC/ESH guidelines for hypertension recommend differential
management of patients who are< 65, 65–79, and≥ 80 years of age. However, it is unclear …

Comprehensive treatment of hypertension middle-aged and elderly people: cross-sectional survey data from the China health and retirement longitudinal study …

S Wang, R Chen, Q Liu, S Zhan, L Li - The Lancet, 2015 - thelancet.com
Background Both drug treatment and non-drug treatment were definitely recommended in
the 2010 Guidelines for Prevention and Treatment of Hypertension in China. This study aims …