[PDF][PDF] Targeting oxidative stress and inflammation in NSAIDs induced gastropathy: a plausible therapeutic approach

K Sinha, PC Sil - Inflamm Cell Signal, 2015 - pdfs.semanticscholar.org
Deregulation in prostaglandin (PG) biosynthesis, oxidative stress, inflammation, and
apoptosis play a major role in the pathogenesis of nonsteroidal anti-inflammatory drug …

Current perspectives in NSAID‐induced gastropathy

M Sinha, L Gautam, PK Shukla, P Kaur… - Mediators of …, 2013 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are the most highly prescribed drugs in the
world. Their analgesic, anti‐inflammatory, and antipyretic actions may be beneficial; …

Rescue strategies against non‐steroidal anti‐inflammatory drug‐induced gastroduodenal damage

YJ Lim, JS Lee, YS Ku, KB Hahm - Journal of Gastroenterology …, 2009 - Wiley Online Library
Non‐steroidal anti‐inflammatory drugs (NSAIDs) are the most commonly prescribed drugs
worldwide, which attests to their efficacy as analgesic, antipyretic and anti‐inflammatory …

An overview of gastropathy induced by nonsteroidal anti-inflammatory drugs: evidence-based pharmacy practice

N Schellack - SA Pharmaceutical Journal, 2012 - journals.co.za
Nonsteroidal anti-inflammatory drugs (NSAIDs) constitute a well-known group of drugs that
are most widely used for a variety of inflammatory conditions and pain. However, their …

Gastroprotective role of glucocorticoids during NSAID-induced gastropathy

L Filaretova - Current pharmaceutical design, 2013 - ingentaconnect.com
Nonsteroidal anti-inflammatory drugs (NSAIDs) make significant contributions to gastric
ulcer disease which remains widespread. Although several factors have been postulated as …

Nonsteroidal anti-inflammatory drug gastropathy at the new millennium: mechanisms and prevention

M Rich, JM Scheiman - Seminars in arthritis and rheumatism, 2000 - Elsevier
Objectives: Nonsteroidal anti-inflammatory drug (NSAID)–induced gastrointestinal (GI)
toxicity remains the most frequent adverse drug event in the United States. The objective of …

[HTML][HTML] Effects of non-steroidal anti-inflammatory drugs (NSAIDs) and gastroprotective NSAIDs on the gastrointestinal tract: a narrative review

R Sohail, M Mathew, KK Patel, SA Reddy, Z Haider… - Cureus, 2023 - ncbi.nlm.nih.gov
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for their anti-
inflammatory, antipyretic, and analgesic properties. However, their use is often associated …

[HTML][HTML] NSAID-associated small intestinal injury: an overview from animal model development to pathogenesis, treatment, and prevention

M Zhang, F Xia, S Xia, W Zhou, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
With the wide application of non-steroidal anti-inflammatory drugs (NSAIDs), their
gastrointestinal side effects are an urgent health burden. There are currently sound …

[HTML][HTML] Mechanisms, prevention and clinical implications of nonsteroidal anti-inflammatory drug-enteropathy

JL Wallace - World Journal of Gastroenterology: WJG, 2013 - ncbi.nlm.nih.gov
This article reviews the latest developments in understanding the pathogenesis, detection
and treatment of small intestinal damage and bleeding caused by nonsteroidal anti …

Mechanisms of damage to the gastrointestinal tract from nonsteroidal anti-inflammatory drugs

I Bjarnason, C Scarpignato, E Holmgren, M Olszewski… - Gastroenterology, 2018 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) can damage the gastrointestinal tract,
causing widespread morbidity and mortality. Although mechanisms of damage involve the …