Methylated ZNF582 as a triage marker for occult cervical cancer and advanced cervical intraepithelial neoplasia

Y Su, Y Tang, T Zhang, Y Xu, Y Zhang, Y Shen… - Future …, 2022 - Taylor & Francis
Aim: To explore the appropriate triage methods for women infected with high-risk human
papillomavirus (hrHPV). Materials & methods: A total of 424 out of 872 hrHPV-infected …

[HTML][HTML] ZNF671 methylation test in cervical scrapings for cervical intraepithelial neoplasia grade 3 and cervical cancer detection

P Zhu, J Xiong, D Yuan, X Li, L Luo, J Huang… - Cell Reports …, 2023 - cell.com
Effective triage of high-risk human papillomavirus (hrHPV)+ women is warranted to avoid
unnecessary referral and overtreatment. Molecular triage tests have recently begun to …

[HTML][HTML] ZNF582 methylation as a potential biomarker to predict cervical intraepithelial neoplasia type III/worse: A meta-analysis of related studies in Chinese …

N Li, Y He, P Mi, Y Hu - Medicine, 2019 - journals.lww.com
Objective: DNA methylation markers have been assessed as potential biomarkers for early
cervical cancer detection. Herein, we evaluated the diagnostic performance of zinc finger …

Methylated ZNF582 gene as a marker for triage of women with Pap smear reporting low-grade squamous intraepithelial lesions—a Taiwanese Gynecologic Oncology …

H Lin, TC Chen, TC Chang, YM Cheng, CH Chen… - Gynecologic …, 2014 - Elsevier
Objective Our previous work revealed that host genes ZNF582, PTPRR, PAX1, and SOX1
are highly methylated in cervical intraepithelial neoplasias grade 3 or worse (CIN3+). In this …

DNA methylation markers as triage test for the early identification of cervical lesions in a Chinese population

N Li, Y Hu, X Zhang, Y Liu, Y He… - … journal of cancer, 2021 - Wiley Online Library
Objective strategies are required in cervical cancer screening. We have identified several
DNA methylation markers with high sensitivity and specificity to detect cervical intraepithelial …

DNA methylation marker for the triage of hrHPV positive women in cervical cancer screening: Real-world evidence in Taiwan

CL Chang, SC Ho, YF Su, YC Juan, CY Huang… - Gynecologic …, 2021 - Elsevier
Objective Human papillomavirus (HPV) testing as the primary cervical cancer screening
followed by reflex cytology if high-risk HPV is present (hrHPV+) is recently adopted in some …

[HTML][HTML] Comparison of HPV genotyping and methylated ZNF582 as triage for women with equivocal liquid-based cytology results

YL Liou, Y Zhang, Y Liu, L Cao, CZ Qin, TL Zhang… - Clinical …, 2015 - Springer
Introduction The interpretation of equivocal Papanicolaou (Pap) smear results remains
challenging, even with the addition of the high-risk human papillomavirus test (HPV-HR) …

Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16/18 genotyping for the detection of cervical (pre)cancer in high‐risk HPV‐positive …

R Luttmer, LMA De Strooper, J Berkhof… - … journal of cancer, 2016 - Wiley Online Library
Recently, DNA methylation analysis of FAM19A4 in cervical scrapes has been shown to
adequately detect high‐grade cervical intraepithelial neoplasia and cervical cancer (≥ …

[HTML][HTML] Cytological DNA methylation for cervical cancer screening: a validation set

L Kong, L Wang, Z Wang, X Xiao, Y You, H Wu… - Frontiers in …, 2023 - frontiersin.org
Background In a previous training set with a case-controlled design, cutoff values for host
EPB41L3 and JAM3 gene methylation were obtained for the detection of cervical …

Combined CADM1/MAL Methylation and Cytology Testing for Colposcopy Triage of High-Risk HPV-Positive Women

LMA De Strooper, AT Hesselink, J Berkhof… - … Biomarkers & Prevention, 2014 - AACR
Primary screening for high-risk human papillomavirus (hrHPV) requires a triage protocol.
Repeat cytology testing at baseline and after 6 to 12 months has emerged as a reasonable …