[HTML][HTML] Pirfenidone ameliorates alcohol-induced promotion of breast cancer in mice

H Li, M Xu, D Chen, W Wen, J Luo - Frontiers in Oncology, 2024 - frontiersin.org
Purpose Alcohol consumption increases the risk of breast cancer and promotes cancer
progression. Alcohol exposure could affect both processes of the mammary carcinogenesis …

[HTML][HTML] Chronic ethanol exposure enhances the aggressiveness of breast cancer: the role of p38γ

M Xu, S Wang, Z Ren, JA Frank, XH Yang, Z Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Both epidemiological and experimental studies suggest that ethanol may enhance
aggressiveness of breast cancer. We have previously demonstrated that short term …

p53 pathway determines the cellular response to alcohol-induced DNA damage in MCF-7 breast cancer cells

M Zhao, EW Howard, Z Guo, AB Parris, X Yang - PLoS One, 2017 - journals.plos.org
Alcohol consumption is associated with increased breast cancer risk; however, the
underlying mechanisms that contribute to mammary tumor initiation and progression are …

Alcohol promotes migration and invasion of triple‐negative breast cancer cells through activation of p38 MAPK and JNK

M Zhao, EW Howard, AB Parris, Z Guo… - Molecular …, 2017 - Wiley Online Library
Although alcohol is an established breast cancer risk factor, the underlying mechanisms
remain unclear. Previous studies examined the general association between alcohol …

ErbB2 and p38γ MAPK mediate alcohol-induced increase in breast cancer stem cells and metastasis

M Xu, Z Ren, X Wang, A Comer, JA Frank, Z Ke… - Molecular cancer, 2016 - Springer
Background Both epidemiological and experimental studies suggest that excessive alcohol
exposure increases the risk for breast cancer and enhances metastasis/recurrence. We …

Effects of the activated mitogen-activated protein kinase pathway via the c-ros receptor tyrosine kinase on the T47D breast cancer cell line following alcohol exposure

HT Lee, SK Kim, MR Choi, JH Park… - Oncology …, 2013 - spandidos-publications.com
Compared to other cancers affecting women, breast cancer is significantly associated with
alcohol consumption. However, the principles underlying the carcinogenesis of alcohol …

Alcohol intake and abnormal expression of Brf1 in breast cancer

C Huang, Y Zhang, S Zhong - Oxidative Medicine and Cellular …, 2019 - Wiley Online Library
Breast cancer is the most common malignant disease of females. Overall, one woman in
every nine will get breast cancer at some time in her life. Epidemiological studies have …

Alcohol regulates genes that are associated with response to endocrine therapy and attenuates the actions of tamoxifen in breast cancer cells

NR Candelaria, R Weldon, S Muthusamy… - PLoS …, 2015 - journals.plos.org
Hereditary, hormonal, and behavioral factors contribute to the development of breast cancer.
Alcohol consumption is a modifiable behavior that is linked to increased breast cancer risks …

Adolescent‐and adult‐initiated alcohol exposure in mice differentially promotes tumorigenesis and metastasis of breast cancer

M Xu, H Li, D Chen, H Wu, W Wen, H Xu… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background Alcohol exposure increases the risk of breast cancer. Alcohol consumption by
adolescents is a serious social and public health issue. This study investigated the impact of …

[HTML][HTML] Tamoxifen represses alcohol-induced transcription of RNA polymerase III-dependent genes in breast cancer cells

Q Zhong, G Shi, Q Zhang, L Lu, D Levy, S Zhong - Oncotarget, 2014 - ncbi.nlm.nih.gov
Alcohol consumption in women has been associated with an increased risk of breast cancer,
particular in estrogen receptor positive (ER+) cases. Deregulation of RNA polymerase III …