[HTML][HTML] New drugs and other strategies for the treatment of fungal infections
R Almeida-Paes, S Frases - Future Microbiology, 2023 - Future Medicine
The field of medical science has long been engaged in a relentless war against microbial
foes, seeking innovative strategies and treatments to combat the ever-evolving threats they …
foes, seeking innovative strategies and treatments to combat the ever-evolving threats they …
Antifungal drug development: challenges, unmet clinical needs, and new approaches
T Roemer, DJ Krysan - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Invasive, life-threatening fungal infections are an important cause of morbidity and mortality,
particularly for patients with compromised immune function. The number of therapeutic …
particularly for patients with compromised immune function. The number of therapeutic …
[HTML][HTML] New horizons in antifungal therapy
KM Pianalto, JA Alspaugh - Journal of Fungi, 2016 - mdpi.com
Recent investigations have yielded both profound insights into the mechanisms required by
pathogenic fungi for virulence within the human host, as well as novel potential targets for …
pathogenic fungi for virulence within the human host, as well as novel potential targets for …
Potential targets for the development of new antifungal drugs
H Su, L Han, X Huang - The journal of antibiotics, 2018 - nature.com
In recent years, incidences of invasive fungal infections have greatly increased, especially in
immunosuppressed patients, but most today's antifungal drugs are not completely effective …
immunosuppressed patients, but most today's antifungal drugs are not completely effective …
Antifungal drugs: the current armamentarium and development of new agents
Invasive fungal infections are becoming an increasingly important cause of human mortality
and morbidity, particularly for immunocompromised populations. The fungal pathogens …
and morbidity, particularly for immunocompromised populations. The fungal pathogens …
[HTML][HTML] Antifungal pipeline
TP McCarty, PG Pappas - Frontiers in cellular and infection …, 2021 - frontiersin.org
In many ways, fungal diseases are forgotten or neglected. Given the significantly lower
frequency compared to similar bacterial etiologies across the spectrum of infectious …
frequency compared to similar bacterial etiologies across the spectrum of infectious …
[PDF][PDF] Hope on the horizon: novel fungal treatments in development
AM Rauseo, A Coler-Reilly, L Larson… - Open forum infectious …, 2020 - academic.oup.com
The treatment of invasive fungal infections remains challenging due to limitations in currently
available antifungal therapies including toxicity, interactions, restricted routes of …
available antifungal therapies including toxicity, interactions, restricted routes of …
Antifungal therapy-state of the art at the beginning of the 21st century
J Müller, A Polak, R Kappe, D Rimek, M Seibold… - … Agents: Advances and …, 2003 - Springer
The most relevant information on the present state of the art of antifungal chemotherapy is
reviewed in this chapter. For dermatomycoses a variety of topical antifungals are available …
reviewed in this chapter. For dermatomycoses a variety of topical antifungals are available …
An update on the global treatment of invasive fungal infections
ME Munzen, AD Goncalves Garcia… - Future …, 2023 - Future Medicine
Fungal infections are a serious problem affecting many people worldwide, creating critical
economic and medical consequences. Fungi are ubiquitous and can cause invasive …
economic and medical consequences. Fungi are ubiquitous and can cause invasive …
Emerging targets for the development of novel antifungal therapeutics
AH Groll, AJ De Lucca, TJ Walsh - Trends in Microbiology, 1998 - cell.com
Invasive mycoses have become important causes of morbidity and mortality in
immunocompromised patients. New approaches for antifungal therapy are required to meet …
immunocompromised patients. New approaches for antifungal therapy are required to meet …