Background RNA methylation modifications, such as N1-methyladenosine/N6-
methyladenosine/N5-methylcytosine (m1A/m6A/m5C), are the most common RNA …

Background Renal interstitial fibrosis (RIF) is the main pathological change of a variety of
chronic kidney diseases (CKD). Epigenetic modifications of fibrosis-prone genes regulate …

Background: During the course of CKD, the patient's renal function continues to deteriorate,
eventually progressing to ESRD. Renal interstitial fibrosis (RIF) is the end result of the …

Background One in eleven people is affected by chronic kidney disease, a condition
characterized by kidney fibrosis and progressive loss of kidney function. Epidemiological …

Objective To investigate the expression profile of RNA m6A in renal fibrosis model of
unilateral ureteral obstruction (UUO) mice and conduct its related bioinformatics analysis, so …

Renal fibrosis plays a crucial role in the progression of renal diseases, yet the lack of
effective diagnostic markers poses challenges in scientific and clinical practices. In this …

Renal interstitial fibrosis (RIF) is a key feature of progressive chronic kidney disease (CKD),
characterized by tubular epithelial cell (TEC) hypoxia and peritubular capillary (PTC) …

Background RNA methylation is a widely known post-transcriptional regulation which exists
in many cancer and immune system diseases. However, the potential role and crosstalk of …

Background Renal interstitial fibrosis (RIF) is the common final pathway that mediates
almost all progressive renal diseases. However, the underlying mechanisms of RIF have not …

Aim: To reveal the alterations of N6-methyladenosine (m6A) epitranscriptome profile in
kidney after unilateral ureteral obstruction in mice. Materials & methods: Total renal m6A and …