Airway inflammation, airflow obstruction, and bronchial hyperresponsiveness are
characteristic phenotypic features of asthma. Clinically, airflow obstruction in asthma often is …

An important advance in our understanding of the pathophysiology of asthma has been the
discovery that airway inflammation is not confined to severe asthma but also characterizes …

Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and
airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to …

Airway remodeling encompasses the structural alterations in asthmatic compared with
normal airways. Airway remodeling in asthmatic patients involves a wide array of …

Airway remodelling refers to the structural changes that occur in the airway wall in asthma.
These include epithelial hyperplasia and metaplasia, subepithelial fibrosis, muscle cell …

Airway remodeling can be defined as changes in the composition, content, and organization
of the cellular and molecular constituents of the airway wall. Airway remodeling is a …

Asthma is an inflammatory disease of the airways that may result from exposure to allergens
or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of …

Asthma is a chronic disease of the airways that has long been viewed predominately as an
inflammatory condition. Accordingly, current therapeutic interventions focus primarily on …

Current strategies for the management of asthma focus on suppressing airway inflammation.
Other characteristic features of human asthma, such as airway hyperreactivity and the …

The inflammatory and remodelling processes that underlie asthma result from a highly
complex interaction between various cell types. Apart from inflammatory cells, such as …