Because of structural and cellular differences (ie, degrees of matrix abundance and cross-
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …

Inflammation and angiogenesis are frequently coupled in pathological situations such as
atherosclerosis, diabetes, and arthritis. The inflammatory response increases capillary …

Vascular remodeling is the adaptive response to various physiological and
pathophysiological alterations that are closely related to aging and vascular diseases …

The e xtra c ellular m atrix (ECM) of the normal artery wall is a collection of fibrous proteins
and associated glycoproteins embedded in a hydrated ground substance of …

The extracellular matrix (ECM) is critical for all aspects of vascular biology. In concert with
supporting cells, endothelial cells (ECs) assemble a laminin-rich basement membrane …

Extracellular matrix (ECM) is essential for all stages of angiogenesis. In the adult,
angiogenesis begins with endothelial cell (EC) activation, degradation of vascular basement …

Extracellular matrix (ECM) within the vascular network provides both a structural and
regulatory role. The ECM is a dynamic composite of multiple proteins that form structures …

Angiogenesis is a multistep process driven by a wide range of positive and negative
regulatory factors. Extracellular matrix (ECM) plays a crucial role in the regulation of this …

Significance: The vascular extracellular matrix (ECM) not only provides mechanical stability
but also manipulates vascular cell behaviors, which are crucial for vascular function and …

The extracellular matrix provides a structural framework essential for the functional
properties of vessel walls. The three dimensional organization of the extracellular matrix …