[HTML][HTML] Precision medicine in catecholaminergic polymorphic ventricular tachycardia: Recent advances toward personalized care

A Siu, E Tandanu, B Ma, EE Osas, H Liu… - Annals of Pediatric …, 2023 - journals.lww.com
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare inherited cardiac
ion channelopathy where the initial disease presentation is during childhood or adolescent …

Catecholaminergic polymorphic ventricular tachycardia: An exciting new era

SP Behere, SN Weindling - Annals of Pediatric Cardiology, 2016 - journals.lww.com
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a highly malignant
inheritable cardiac channelopathy. The past decade and a half has provided exciting new …

Pediatric catecholaminergic polymorphic ventricular tachycardia: a translational perspective for the clinician-scientist

D Kallas, A Lamba, TM Roston, A Arslanova… - International journal of …, 2021 - mdpi.com
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare and potentially
lethal inherited arrhythmia disease characterized by exercise or emotion-induced …

The clinical and genetic spectrum of catecholaminergic polymorphic ventricular tachycardia: findings from an international multicentre registry

TM Roston, Z Yuchi, PJ Kannankeril, J Hathaway… - Ep …, 2018 - academic.oup.com
Aims Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an ion
channelopathy characterized by ventricular arrhythmia during exertion or stress. Mutations …

Catecholaminergic Polymorphic Ventricular Tachycardia: Clinical Characteristics, Diagnostic Evaluation and Therapeutic Strategies

A Aggarwal, A Stolear, MM Alam, S Vardhan… - Journal of Clinical …, 2024 - mdpi.com
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a severe hereditary
arrhythmia syndrome predominantly affecting children and young adults. It manifests …

Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry

TM Roston, O Haji-Ghassemi, MJ LaPage, AS Batra… - PLoS …, 2018 - journals.plos.org
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is often a life-
threatening arrhythmia disorder with variable penetrance and expressivity. Little is known …

New exome data question the pathogenicity of genetic variants previously associated with catecholaminergic polymorphic ventricular tachycardia

J Jabbari, R Jabbari, MW Nielsen… - Circulation …, 2013 - Am Heart Assoc
Background—Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal,
rare hereditary disease with an estimated prevalence of 1: 10 000. The genetic variants that …

Catecholaminergic polymorphic ventricular tachycardia: a model for genotype-specific therapy

TM Roston, F Van Petegem… - Current opinion in …, 2017 - journals.lww.com
CPVT is usually related to RyR2 or associated proteins. Emerging studies reveal several
genotype–phenotype correlations, which may eventually influence therapeutic decision …

Precision Medicine in Catecholaminergic Polymorphic Ventricular Tachycardia: JACC Focus Seminar 5/5

SG Priori, A Mazzanti, DJ Santiago, D Kukavica… - Journal of the American …, 2021 - jacc.org
In this final of a 5-part Focus Seminar series on precision medicine, we focus on
catecholaminergic polymorphic ventricular tachycardia (CPVT). This focus on CPVT allows …

[PDF][PDF] Catecholaminergic Polymorphic Ventricular Tachycardia and Gene Therapy: A Comprehensive Review of the Literature

E Henriquez, EA Hernandez, SR Mundla… - Cureus, 2023 - cureus.com
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited
channelopathy. In this review, we summarize the epidemiology, pathophysiology, clinical …